March 2024 in “Frontiers in Endocrinology” In this study, a bidirectional Mendelian randomization analysis found a causal link between alopecia areata and hypothyroidism, indicating that each condition may influence the other, while no similar relationship was observed between androgenetic alopecia and hypothyroidism.
1 citations
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August 2021 in “Arhivʺ vnutrennej mediciny” This review discusses the role of hormones and other factors in the development of alopecia linked to endocrine disorders, but reports no new clinical results, emphasizing the need for a multidisciplinary diagnostic approach.
18 citations
,
March 2016 in “Cosmetics” This review discusses telogen effluvium, including its triggers, clinical presentations, and management options, and does not report new research findings, emphasizing the need for identification and exclusion of underlying causes.
3 citations
,
June 2020 in “Cureus” This case study highlights a 36-year-old woman with alopecia areata who experienced near complete hair regrowth after intralesional triamcinolone acetonide; further investigation revealed a systemic lupus erythematosus diagnosis.
This source reports that telogenic hair loss, while not leading to complete baldness, significantly impacts patients' quality of life due to its effects on their psychoemotional state; no standardized treatment currently exists, so therapy focuses on addressing trigger factors and psychological well-being.
July 2024 in “Medical alphabet” In this review, researchers discuss the factors contributing to early graying, such as genetic predisposition, oxidative stress imbalance, and nutrient deficiencies, and highlight potential restoration methods involving palmitoyl tetrapeptide-20 and the endocannabinoid system in hair follicles.
February 2024 in “Biomedicines” This review examines the hormonal causes of hair loss, noting how androgen excess can lead to follicle miniaturization and linking estrogen deficiency and thyroid dysfunction to common alopecia types. It further discusses hormonal treatments such as finasteride, dutasteride, and spironolactone.
August 2022 in “Our Dermatology Online” This study found that dermoscopy can help differentiate between types of diffuse alopecia in females, with yellow dots common in telogen effluvium and hair diameter diversity over 20% significant in female androgenetic alopecia.
276 citations
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April 2003 in “Molecular endocrinology” This review explores the diverse physiological roles of the vitamin D endocrine system, discussing current research on receptor structure, transcription details, murine models, and alternative receptors, but reports no new findings.
78 citations
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November 2005 in “Endocrinology” This study found that Hairless (Hr) acts as a corepressor of the vitamin D receptor (VDR) in human keratinocytes, blocking the action of vitamin D on keratinocyte differentiation.
February 2023 in “European journal of geriatrics and gerontology” Selenium helps prevent thyroid issues and cognitive decline in the elderly, but balance is key.
25 citations
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June 2019 in “Endocrine Related Cancer” This review discusses the structure and function of steroid nuclear receptors, particularly focusing on androgen receptor dysregulation in prostate cancer and androgen insensitivity syndromes, without reporting new experimental results.
1 citations
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August 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” This study reports that a novel gain-of-function mutation in TMEM173, combined with polymorphisms in TMEM173 and IFIH1, results in a distinct clinical phenotype with features of SAVI, including alopecia and photosensitivity.
2 citations
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January 2023 in “Journal of Clinical Medicine” This review discusses the links between different types of alopecia and thyroid disorders, highlighting some shared autoimmune factors, but reports no new clinical results.
December 2019 in “Mehmet Akif Ersoy Üniversitesi Sağlık Bilimleri Enstitüsü dergisi” In this case series, two cats with hypothyroidism and hyperthyroidism achieved clinical remission and normal thyroid function following timely diagnosis and targeted treatment with levothyroxine and methimazole, respectively.
10 citations
,
January 2009 in “Elsevier eBooks” This review discusses the structure, functions, and growth cycle of human hair, emphasizing its reduced growth and protective roles, and reports no new research findings.
100 citations
,
July 2004 in “The Journal of Sexual Medicine” This article reviews how various hormones may affect female sexual function and provides recommendations for diagnosing and treating endocrinologic sexual difficulties, but it reports no new clinical results.
5 citations
,
June 2021 in “Pharmacological Reports” This study suggests that vitamin D treatment may be less effective in reducing thyroid autoimmunity for euthyroid men with early-onset androgenic alopecia compared to other men with autoimmune thyroiditis.
January 2021 in “Indian Journal of Pharmaceutical Sciences” This study found that diode and alexandrite laser hair removal systems did not significantly impact thyroid hormone concentrations, hemoglobin, or bilirubin levels in women undergoing facial hair treatment.
32 citations
,
March 2021 in “Journal of endocrinological investigation” This review covers the connection between thyroid diseases and skin conditions like alopecia, dermatitis, and vitiligo, and highlights the need for further research on the role of thyroid hormones in skin health.
11 citations
,
April 2021 in “Journal of Clinical Medicine” This study found that long-term use of a home-use LED device for neck skin rejuvenation significantly improved wrinkle appearance and skin biophysical parameters without affecting thyroid function or morphology after 16 weeks of daily use.
7 citations
,
October 2020 in “Wiener medizinische Wochenschrift” This paper presents a case study of a 21-year-old male with thyroid hemiagenesis, where the left thyroid lobe and isthmus are absent, and discusses the anomaly's potential clinical consequences based on existing literature.
June 2024 in “Biological and Clinical Sciences Research Journal” In this study, researchers found that women with PCOS and thyroid dysfunction had significantly altered T3 and T4 hormone levels and more frequent symptoms like weight gain and irregular menstrual cycles, suggesting the importance of thyroid screenings for personalized treatment strategies.
January 2024 in “Medicine” This retrospective study of 500 female patients with telogen effluvium found that those with hypothyroidism had more severe hair loss compared to those with normal thyroid function or hyperthyroidism, highlighting the importance of thyroid function testing in these cases.
1540 citations
,
October 2008 in “Fertility and Sterility” This review discusses the definition of polycystic ovary syndrome proposed by the AE-PCOS Society Task Force, emphasizing hyperandrogenism, ovarian dysfunction, and excluding related disorders, while noting potential variations needing more research.
120 citations
,
November 2014 in “Biological Reviews” This article explores the dynamic and energy-efficient nature of telogen hair follicles, challenging the notion of dormancy, and highlights their potential in advancing treatments for hair growth disorders.
69 citations
,
January 2013 in “Frontiers in Immunology” This review summarizes existing knowledge on the role of FOXN1 as a key regulator of thymic epithelial cell lineage and function, reporting no new experimental results.
30 citations
,
October 2012 in “Current Opinion in Endocrinology, Diabetes and Obesity” This review discusses the effects of thyroid hormone on the skin and explores the potential for using it to treat skin diseases, but reports no new clinical results.
34 citations
,
June 2010 in “Archives of Disease in Childhood” This review discusses normal menstrual variations and common menstrual disorders in adolescent girls, focusing on symptoms, evaluation, and management, but does not present new clinical results.
24 citations
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July 2011 in “PubMed” This review discusses the classic skin characteristics of hypothyroidism, notably generalized myxedema caused by increased glycosaminoglycan deposition, and reports no clinical results.