December 2016 in “Journal of evolution of medical and dental sciences” This study reported common skin changes and symptoms associated with thyroid disorders, such as dry skin in hypothyroidism and warm, soft skin in hyperthyroidism, and noted urticaria as a frequent autoimmune association in hypothyroid patients.
December 2025 in “International Journal of Medicine and Public Health” In this study, researchers found that overt hyperthyroidism was the most prevalent thyroid disorder among patients, especially in women, and it was characterized by classic symptoms like high pulse rate and weight loss, highlighting the importance of early identification and management to prevent complications.
September 2025 in “Cutaneous and Ocular Toxicology” In this study, researchers found no significant differences in serum levels of ferritin, folate, vitamin B12, vitamin D, or thyroid function between patients with scarring alopecia and healthy controls, suggesting these factors may not play a major role in the disease's pathogenesis.
16 citations
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January 2017 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that premature hair graying is strongly associated with a family history, Vitamin B12 deficiency, and hypothyroidism, with onset as early as 5 years in patients in Gurugram, India.
6 citations
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January 2012 in “Annals of Indian Academy of Neurology” This study found that women with epilepsy on carbamazepine and sodium valproate monotherapy experienced more significant weight gain but showed no difference in PCOS incidence compared to phenytoin users; elevated TSH levels were more common among those on sodium valproate.
April 2026 in “International Journal of Homoeopathic Sciences” This narrative review found a strong association between alopecia areata and autoimmune thyroid diseases, suggesting routine thyroid function and autoantibody screening could be beneficial for certain patients with extensive, recurrent, or early-onset alopecia areata.
January 2024 in “Indian Journal of Pharmacy Practice” This study examined 142 patients with subclinical thyroid disorders and found a high incidence of comorbidities like renal diseases. Researchers reported that good medication adherence was associated with better quality of life, indicating a significant relationship between adherence and quality of life.
January 2022 in “Indian journal of dermatopathology and diagnostic dermatology” This study observed that low serum ferritin and vitamin D levels may contribute to diffuse hair loss in women.
35 citations
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October 2017 in “JAMA dermatology” This study recommends limiting routine thyroid function screening to children with alopecia areata who have medical histories of Down syndrome, atopy, or family histories of thyroid disease.
August 2024 in “Journal of Cosmetic Dermatology” This study investigates differences in nutritional status, vitamin, and mineral levels between individuals with telogen effluvium and a control group, aiming to understand the nutritional factors involved in this condition.
November 2023 in “Ibrahim Cardiac Medical Journal” This study observed that patients with alopecia areata have a significantly higher prevalence of thyroid disorders and elevated levels of thyroid-stimulating hormone and thyroid auto-antibodies compared to healthy individuals, with a 4.7 times greater risk of thyroid dysfunction among alopecia areata patients.
May 2022 in “Endocrine practice” This case report illustrates that high-dose biotin supplementation can cause false thyroid function test abnormalities in vitro, emphasizing the need to assess biotin intake before testing.
This study found that specific and nonspecific skin changes can serve as important indicators for diagnosing thyroid diseases, even in patients who appear clinically normal.
178 citations
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October 2001 in “Genes & Development” This study found that the mammalian hairless gene encodes a corepressor protein that interacts with thyroid hormone receptors, providing insights into hair loss syndromes in humans and mice.
49 citations
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December 2009 in “Journal of Investigative Dermatology” This review explores the complex relationship between thyroid hormones and skin, discussing potential mechanisms and known interactions but reports no new clinical results, emphasizing the need for further research.
November 2025 in “International Journal of Pharmaceutical Sciences and Drug Research” In this study, thyroid disorders were found to significantly affect physical and emotional well-being, with notable prevalence in married, urban, and non-working participants in South India.
October 2023 in “Clinical medicine and medical research” This study indicates that higher thyroid-stimulating hormone levels may be linked to post-COVID-19 hair loss in women, while ferritin levels showed no significant correlation.
September 2023 in “Medical and Clinical Case Reports” This source explores the association between alopecia areata and thyroid dysfunction, highlighting a particularly strong link with Hashimoto thyroiditis and hypothyroidism.
6 citations
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October 2020 in “Endocrine journal” This case report identifies two specific mutations in the WRN gene in a 40-year-old female with Werner syndrome, highlighting the need for awareness of its early manifestations and treatment options.
April 2025 in “International Journal of Research in Dermatology” This study investigated cutaneous manifestations in thyroid disorder patients, finding that hypothyroid patients commonly experienced dry skin (67.83%) while warm skin (93.3%) and increased sweating prevailed in hyperthyroid patients, with urticaria being the most common autoimmune association among both groups.
This study reviewed existing literature to demonstrate that thyroid disorders have a significant and underestimated impact on hair loss, highlighting gaps in current knowledge and the need for further research to better diagnose and manage hair disorders linked to thyroid dysfunction.
11 citations
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October 2011 in “Dermato-endocrinology” This study revealed that manual thyroid examinations in alopecia patients may uncover thyroid abnormalities undetectable by blood tests alone, but further research is needed to assess their clinical importance.
24 citations
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June 2018 in “Reviews in endocrine and metabolic disorders” This review discusses the epidemiology, clinical manifestations, and pathogenesis of autoimmune skin diseases and their associations with thyroid diseases, reporting no new clinical results.
5 citations
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July 2020 in “Curēus” This case study reports complete beard hair regrowth in a man with beard alopecia areata after six months of treatment with 0.1% triamcinolone acetonide cream.
1 citations
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January 2021 in “Acta dermatovenerologica Alpina, Pannonica et Adriatica (Tiskana izd.)” This report suggests a potential link between hyperprolactinemia and alopecia in women with autoimmune thyroid disease and emphasizes the importance of considering other causes in diagnosis.
7 citations
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October 2012 in “S. Karger AG eBooks” This review discusses the similarities in clinical, endocrine, and ultrasonographic features between PCOS and other disorders with excessive androgen secretion, emphasizing the importance of accurate diagnosis but reports no new clinical results.
27 citations
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July 2015 in “International Journal of Dermatology” This study found that skin disorders are prevalent among elderly individuals and are often associated with underlying systemic diseases.
11 citations
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July 2012 in “Current Opinion in Pediatrics” This review discusses dermatologic signs in childhood endocrine disorders and highlights their importance in early diagnosis and treatment, but it reports no new clinical findings.
2 citations
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September 2007 in “International Journal of Impotence Research” This case study reports that low-dose testosterone therapy improved libido and sexual functions in a 36-year-old fragile X carrier female with hypoactive sexual desire disorder when monitored regularly for lab parameters.
2 citations
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May 2006 in “Women's Health Medicine” This article provides an overview of ovulation disorders, discussing ovarian, hypothalamic, and endocrine defects but reports no new clinical findings.