October 2024 in “Journal of the Pakistan Medical Association” This letter discusses the various risk factors associated with premature greying of hair, highlighting genetic predispositions, nutritional deficiencies, stress, and lifestyle factors, while noting a lack of conclusive data on effective interventions, as detailed in the reviewed studies.
July 2024 in “Medical alphabet” In this review, researchers discuss the factors contributing to early graying, such as genetic predisposition, oxidative stress imbalance, and nutrient deficiencies, and highlight potential restoration methods involving palmitoyl tetrapeptide-20 and the endocannabinoid system in hair follicles.
June 2026 in “kerbala journal of pharmaceutical sciences” In this case-control study, individuals with alopecia areata showed significantly elevated levels of inflammatory markers IL-4, IFN-γ, and CRP, as well as reduced serum Folate and Ferritin, suggesting the condition's multifactorial pathophysiology involves immune activation, systemic inflammation, and micronutrient deficiencies.
October 2025 in “Diseases” This study reports that women with hair loss had significantly lower levels of several biomarkers, including hemoglobin, iron, copper, selenium, vitamin D, vitamin B12, folate, and thyroid hormones, compared to healthy controls.
August 2024 in “Journal of Cosmetic Dermatology” This study investigates differences in nutritional status, vitamin, and mineral levels between individuals with telogen effluvium and a control group, aiming to understand the nutritional factors involved in this condition.
43 citations
,
July 2024 in “Nutrients” This narrative review highlights the crucial role of micronutrients and gut microbiota in thyroid function and suggests that nutritional imbalances may contribute to thyroid dysfunction or diseases.
10 citations
,
August 2021 in “Journal of Cosmetic Dermatology” This study retrospectively analyzed 3028 patients with telogen effluvium, finding that 6.2% had iron deficiency anemia and vitamin D deficiency was common, especially in women who were more often prescribed vitamin D therapy.
4 citations
,
November 2009 in “Medical Clinics of North America” This article discusses how changes in hair and nails may indicate systemic diseases, but it provides no new results; the authors emphasize their usefulness in clinical diagnosis.
This source reports that telogenic hair loss, while not leading to complete baldness, significantly impacts patients' quality of life due to its effects on their psychoemotional state; no standardized treatment currently exists, so therapy focuses on addressing trigger factors and psychological well-being.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This study discusses various causes and treatments of hair loss, with a focus on the potential effectiveness of Ayurvedic and synthetic methods, but emphasizes that more research is needed for specific conditions like Telogen Effluvium.
October 2025 in “Journal of the Endocrine Society” This case report describes a 36-year-old female patient with panhypopituitarism, experiencing severe adrenal insufficiency and thyroid hormone deficiency, which led to electrolyte imbalance, QT interval prolongation, and ventricular tachycardia; treatment stabilized her condition, underscoring the importance of hormonal evaluation in arrhythmia assessment.
June 2023 in “British journal of dermatology/British journal of dermatology, Supplement” In this report, a 46-year-old woman's sudden diffuse hair loss was diagnosed as granulomatous alopecia areata, with spontaneous hair regrowth observed after two months. This case highlights that granulomatous inflammation should not exclude the diagnosis of alopecia areata, emphasizing the importance of clinicopathological correlation.
December 2009 in “DergiPark (Istanbul University)” This study found that low levels of ferritin and iron were common among women with diffuse hair loss, suggesting these tests could be useful in evaluating such patients.
2 citations
,
June 1980 in “International Journal of Dermatology” This article on pediculosis lacks an abstract and does not report new research findings.
24 citations
,
July 1987 in “Dermatologic Clinics” This article reviews various causes of hair loss linked to systemic factors, noting that careful history and examination can lead to accurate diagnosis, but reports no new clinical results.
2 citations
,
August 2020 in “Dermatologic Therapy” This analysis from Egyptian researchers identified common risk factors associated with chronic telogen effluvium in children, but it reports no new clinical results.
2 citations
,
January 2019 in “International Journal of Medicine in Developing Countries” This review discusses telogen effluvium as a common cause of diffuse hair loss and reports no new clinical results, noting diagnostic and treatment challenges.
March 2025 in “Nepal Journal of Dermatology Venereology & Leprology” This study observed that Nepalese dermatologists commonly manage telogen effluvium with counseling and supplements, despite the lack of a consensus management guideline.
This chapter reviews management strategies for telogen effluvium, detailing the use of topical and low-dose oral minoxidil, and highlights the importance of screening for secondary causes.
November 2022 in “Journal of the Endocrine Society” This case study reports that immunotherapy with ipilimumab and nivolumab induced hypophysitis in a patient with renal cell carcinoma, emphasizing the need for careful monitoring of endocrine function in such treatments.
January 2022 in “Journal of family medicine” This case report highlights the challenges of misdiagnosis in women with PCOS and emphasizes the importance of a holistic approach to address interconnected endocrine and reproductive dysfunctions.
13 citations
,
August 2020 in “Mayo Clinic proceedings” In this study, women with lichen planopilaris were found to have high rates of thyroid disease, depression, and anxiety, and about half experienced slowed or stabilized disease progression with treatment.
1 citations
,
January 2021 in “International journal of pharmaceutical research” This study found that reduced levels of ferritin, TSH, and hemoglobin in young women and lower TSH, vitamin B12, and vitamin D in older women are associated with chronic diffuse hair loss.
April 2021 in “The journal of heart and lung transplantation/The Journal of heart and lung transplantation” This case report describes a woman with Sheehan's syndrome, leading to severe combined systolic and diastolic heart failure, where treatment improved cardiac function.
21 citations
,
September 2018 in “International journal of women’s dermatology” In this study, patients with lichen planopilaris showed higher prevalence of autoimmune disorders like Hashimoto's thyroiditis and hypothyroidism compared to those with seborrheic dermatitis.
August 2023 in “Tzu Chi Medical Journal” This study at a medical center in Eastern Taiwan found that female alopecia has diverse causes, including nutrient deficiencies, autoimmune diseases, psychological stress, thyroid conditions, and COVID-19 vaccination, with iron deficiency affecting 70.3% of cases.
1 citations
,
January 2018 This review discusses factors affecting thyroid function and Hashimoto's thyroiditis, mentioning treatment options, but reports no new clinical findings; the need for nutrient consideration is emphasized.
January 2021 in “İzmir Dr.Behçet Uz çocuk hastanesi dergisi” This study found that children with alopecia areata had significantly lower levels of vitamin D and B12, and higher thyroid-stimulating hormone and free T4 levels compared to healthy children.
In this case report, a 59-year-old woman experienced burning sensations and developed atrophic, hypopigmented, ivory papules and plaques on her palms and soles over three years, which worsened after walking for extended periods.
January 2024 in “Pediatrics International” In this case study, a 6-year-old boy with autism spectrum disorder developed iodine deficiency hypothyroidism due to extreme picky eating, illustrating the need for flexible dietary interventions in similar cases.