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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Androgens can both increase and decrease hair growth in different parts of the body.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

Targeted cancer therapies often cause serious skin problems that need careful management.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

Oestrogens are key for bone growth during puberty in both boys and girls.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

High androgen levels in young women with PCOS are linked to higher blood pressure.

CDP is crucial for lung and hair follicle cell development.

Latanoprost can make eyelashes longer, thicker, and darker.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Alopecia areata causes hair loss, has no cure, and various treatments exist.

Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.

The HR protein helps hair grow by blocking a hair growth inhibitor, aiding in hair follicle regeneration.

Obesity is linked to various skin problems and may increase the risk of skin cancer.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

Manipulating the catagen and telogen phases of hair growth could lead to treatments for hair disorders.

Women with epilepsy should be monitored for reproductive issues, which can be caused by epilepsy or its treatments, especially when using valproate.