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Removing the ATR gene in adult mice causes rapid aging and stem cell loss.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Natural products in cosmetics are beneficial for skin and hair care with low toxicity.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

A protein from certain immune cells is key for new hair growth after skin injury in mice.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

Hair follicle development and microbes help regulatory T cells gather in newborn skin.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

Scientists found a new, less invasive way to study body clocks using hair cells, which shows shift workers' body clocks don't match their lifestyles.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

Cathepsin L is essential for normal hair growth and development.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

No single treatment is consistently effective for alopecia areata, and more research is needed.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Children with atopic dermatitis often have sleep problems, affecting their growth and behavior.

Hair, teeth, and mammary glands develop similarly at first but use different genes later.

Fetal wound healing changes with development, affecting inflammation and collagen, which may influence scarring.

Drospirenone is a unique progestin with anti-water retention and potential blood pressure benefits, used in birth control and hormone therapy.

Cystatin M/E strongly inhibits cathepsin V and cathepsin L, important for skin formation.

Thymosin β4 promotes hair growth by activating stem cells in hair follicles.

The p75 neurotrophin receptor is important for hair follicle regression by controlling cell death.

Prolactin affects hair growth cycles and can cause early hair follicle regression.