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Common acne treatments can cause various side effects, like skin irritation and more serious issues, but combination therapies are often more effective and better tolerated.

Isotretinoin effectively reduces acne but causes dry skin, higher skin pH, more redness, and hair loss.

Finasteride and minoxidil are effective FDA-approved treatments for androgenetic alopecia.

AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.

Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

High glucocorticoids cause pancreatic malfunction and malabsorption, reversible with enzyme supplements.

SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.

Human scalp hair follicles can be used to study how prolactin affects hair growth and cell death.

Adult stem cells with Tp63 can form hair and skin cells when placed in new skin, showing they have hidden abilities for skin repair.

Some thymic peptides can increase human hair growth, while others may inhibit it.

KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.

Medicinal plants like Aloe, Amla, and Coconut oil help with hair and skin care.

Finasteride has different absorption and metabolism in male and female rats, with higher concentrations in certain organs and mostly excreted through feces.

Some herbal ingredients like linalool and tea tree oil have anti-dandruff properties and are safe for use in shampoos.

Proper care and diet are crucial to prevent health issues in gerbils.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

Removing the ATR gene in adult mice causes rapid aging and stem cell loss.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

The conclusion is that certain cell interactions and signals are crucial for hair growth and regeneration.

Hair follicle development and microbes help regulatory T cells gather in newborn skin.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Children with atopic dermatitis often have sleep problems, affecting their growth and behavior.

Drospirenone is a unique progestin with anti-water retention and potential blood pressure benefits, used in birth control and hormone therapy.

Cystatin M/E strongly inhibits cathepsin V and cathepsin L, important for skin formation.

Thymosin β4 promotes hair growth by activating stem cells in hair follicles.