16 citations
,
December 2019 in “Animals” In this study, cashmere goats engineered to overexpress the Tβ4 gene in hair follicles produced more cashmere, indicating that Tβ4 promotes secondary hair follicle development and enhances yield.
11 citations
,
December 2010 in “American journal of transplantation” This study describes three female islet transplant recipients who unexpectedly developed alopecia areata about 7 years post-transplant, with a possible link to immunosuppressive treatment regimens.
11 citations
,
September 1999 in “Journal of the European Academy of Dermatology and Venereology” This review examines various immunomodulatory therapies for cutaneous lymphoma and notes that they are most effective in the disease's early stages.
10 citations
,
December 2018 in “Internal Medicine” This study reports two cases of myasthenia gravis patients with thymoma who exhibited various autoimmune symptoms including alopecia, suggesting a link between thymus-related immune dysregulation and comorbid conditions.
7 citations
,
August 2020 in “Plastic and reconstructive surgery. Global open” In this study, QR 678 and QR 678 Neo formulations containing growth factors and peptides were found to be safe in vitro and promoted hair growth in vivo in an animal model, suggesting their potential as treatments for alopecia, including secondary alopecia post-chemotherapy.
7 citations
,
March 2012 in “Journal of Investigative Dermatology” This study presents evidence that specific thymus-derived peptides affect human hair follicle growth, identifying thymulin as a potential hair growth stimulator despite interindividual response variations.
5 citations
,
April 2024 in “BMC Neurology” The researchers reported that non-motor symptoms like taste disorders and alopecia are associated with myasthenia gravis, particularly in severe cases and those linked to thymoma.
3 citations
,
April 2025 in “Journal of Feline Medicine and Surgery” In this review, the authors examined the clinical presentations, differential diagnoses, and management strategies for feline immune-mediated skin diseases, focusing on conditions like pemphigus complex and cutaneous lupus erythematosus, highlighting that despite their rarity, these diseases can lead to severe systemic issues in cats.
3 citations
,
February 2005 in “Expert Opinion on Investigational Drugs” This review discusses investigational treatments for androgenetic and chemotherapy-induced alopecia and reports no new clinical results, highlighting the need for further research.
1 citations
,
February 2023 in “Ibrain” This review discusses the neuroprotective properties of Nigella sativa and its nanoformulations for treating neurodegenerative disorders, without presenting new clinical results.
July 2026 in “Current Trends in Biotechnology and Pharmacy” In this study, a new herbal hair oil formulation, consisting of plant-derived antifungal agents and natural stabilizers, was developed and demonstrated strong antifungal activity, skin compatibility, and additional hair health benefits in preclinical evaluations, offering a potential alternative for managing fungal scalp infections.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review highlights the therapeutic potential of Ziziphus mauritiana and Black Seed Oil in herbal hair care products, reporting their antioxidant, antimicrobial, and anti-inflammatory properties, which may help address issues like hair fall and scalp irritation while serving as promising natural alternatives to synthetic solutions.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review concludes that herbal formulations containing Ziziphus mauritiana and Black Seed Oil may offer a promising natural alternative for managing hair-related issues like dandruff, hair fall, and scalp irritation.
April 2026 in “Biomedical Materials” In this study, gold nanoparticle-conjugated curcumin and thymoquinone formulations were more effective against melanoma cells in 3D bioprinted scaffolds than free or co-administered phytochemicals, sustaining stress responses and overcoming tumor adaptation barriers.
March 2026 in “Journal of Zhejiang University (Medical Sciences)” This study reported that in mice with rapamycin-induced thymic atrophy, Angelica sinensis promoted thymic cortical regeneration and functional recovery by activating the Wnt/CTNNB1/Foxn1 signaling pathway and improving inflammatory microenvironment, suggesting its potential benefit against immune aging.
August 2019 in “Journal of Invertebrate Pathology” This study observed that different alkaline buffers had a significant impact on the volume of liquid consumed by fall armyworm larvae, emphasizing the importance of measuring imbibed volumes to reduce dose errors in bioassays.
May 2018 in “The journal of immunology/The Journal of immunology” This study identified that patients with compound heterozygous mutations in FOXN1 exhibited severe T-cell lymphopenia but retained normal hair and nail development, indicating a distinct clinical phenotype from classic FOXN1 cases.
October 2016 in “Veterinary record case reports” This article describes a case of feline exfoliative dermatitis associated with a suspected thymoma, diagnosed using histopathology and imaging, and does not report new research findings beyond the case description.
May 2014 in “The journal of immunology/The Journal of immunology” In this study, over-expression of FoxN1 in early life was associated with detrimental effects on thymic and skin epithelial development in mice.
October 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Thymic peptides can either promote or inhibit human hair growth.
This review explores the mechanisms and clinical applications of thymosin β4, highlighting its potential in various medical fields, but it presents no new research findings.
February 1990 in “Journal of The American Academy of Dermatology” This review summarizes therapeutic advances reported in English-language literature from December 1987 to December 1988 and states no new clinical results.
105 citations
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December 2003 in “Veterinary Dermatology” This review discusses the association between cutaneous paraneoplastic syndromes and internal malignancies, noting that recognition of these skin disorders may help detect underlying cancers, but reports no new research findings.
10 citations
,
November 2023 in “Science Immunology” This study found that deleting specific super-enhancer regions in mice affects CD25 expression in a cell type-specific manner, leading to autoimmune alopecia in some cases and revealing distinct regulatory mechanisms for constitutive and inducible expression of CD25.
5 citations
,
March 2015 in “Clinical and Experimental Dermatology” This case report describes a 22-year-old woman who developed persistent, non-scarring hair loss and premature ovarian failure following a myeloablative umbilical cord transplant for acute myeloid leukemia.
1 citations
,
January 2021 in “Journal of Cancer Therapy” This article reviews regenerative medicine strategies, such as stem cells and plant polyphenols, for mitigating radiotherapy side effects but does not present new clinical findings, calling for further investigation.
January 2008 in “Vestnik Tomskogo gosudarstvennogo universiteta Filologiya” This study found that overexpressing thymosin beta-4 in transgenic cashmere goats could potentially increase cashmere yield by boosting the number of secondary hair follicles.
49 citations
,
November 2012 in “Journal of neurology, neurosurgery and psychiatry” This review discusses non-motor symptoms in patients with thymoma-associated myasthenia gravis, suggesting these symptoms, which can be treatable, often go overlooked despite affecting multiple organs.
288 citations
,
January 2001 in “Journal of Biological Chemistry” In this study, the disruption of Gh/tissue transglutaminase in mice did not affect viability but reduced thymocyte viability and fibroblast adhesion, suggesting its role in cell stabilization and extracellular matrix interactions.
688 citations
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June 2007 in “Cell Stem Cell” This study found that deleting the ATR gene in adult mice led to rapid onset of age-related traits such as hair graying and osteoporosis through reduced regenerative capacity.