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Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.

Thymosin β4 promotes hair growth by activating stem cells in hair follicles.

Chronic inflammatory skin diseases are caused by disrupted interactions between skin cells and immune cells.

New technologies help us better understand how skin microbes affect skin diseases.

Skin issues can indicate immune system problems.

Trichohyalin is also found in the outer layers of normal human skin.

Dupilumab is being tested for many new skin, respiratory, and gastrointestinal conditions.

Acne is a temporary skin imbalance during puberty that often resolves on its own.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Type 2 immunity helps control mite growth in hair follicles, preventing damage.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Female donor to male recipient sex mismatch and positive ACA-IgG are key risk factors for vitiligo and alopecia areata in chronic GvHD patients.

Thermoresponsive nanogels show promise for delivering medicine through the skin but need more safety testing and regulatory approval before clinical use.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Exosomes could be key in treating skin conditions and healing wounds.

New treatments like nanotechnology show promise in improving skin cancer therapy.

Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.

Notch signaling is essential for healthy skin and hair follicle maintenance.

Autophagy changes the protein makeup of hair.

Psoriasis involves immune and genetic factors, and understanding these can improve treatments.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

New protein changes may be involved in the immune attack on hair follicles in alopecia areata.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Vitamin D is crucial for skin health and managing skin diseases.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Thermal spring waters and their microbes could be good for skin health and treating some skin conditions in skincare products.