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Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Regenerated fully functional hair follicles using stem cells, with potential for hair regrowth therapy.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.

Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.

Cathepsin L is essential for normal hair growth and development.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

RNAi-based biopesticides could be safe and effective for pest control with careful development and risk assessment.

Transplant success has improved with better immunosuppressive drugs and donor matching.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.

Thymus transplantation successfully restored immune function in infants with FOXN1 deficiency.

Thymosin β4 promotes hair growth by activating stem cells in hair follicles.

Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

New treatments for Alopecia Areata, like JAK inhibitors, show promise for hair regrowth and are likely to change future treatment approaches.

Targeting the skin's endocannabinoid system could help treat skin disorders.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

Zinc deficiency in children can cause skin issues and can be serious if not diagnosed and treated properly.

Biotin treatment can significantly improve hair loss and motor functions in certain metabolic disorders.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

The study identified and characterized new keratin genes linked to hair follicles and epithelial tissues.

Blocking IL-12/IL-23p40 helped reverse severe hair loss in patients.

Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.

Msx2 and Foxn1 are both crucial for hair growth and health.