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Systematic end-of-trial biopsies are the most reliable way to assess outcomes.

This study identified hemoglobin level as the strongest biological predictor of fatigue in systemic lupus erythematosus patients, highlighting its association with disease activity and systemic inflammation.

Hair diameter diversity helps assess hair loss, but its standard measure varies by individual and ethnicity.

In this review, researchers discuss the factors contributing to early graying, such as genetic predisposition, oxidative stress imbalance, and nutrient deficiencies, and highlight potential restoration methods involving palmitoyl tetrapeptide-20 and the endocannabinoid system in hair follicles.

Lack of zinc can cause hearing loss by damaging important parts of inner ear cells in mice.

This study describes a new method using ImageJ to quantitatively assess hair loss in mice with alopecia areata, offering a more precise and reproducible alternative to traditional visual scoring systems by employing image-based analysis techniques.

In this study, no significant change in androgen receptor gene expression was found in females with recurrent spontaneous abortion, but a mutant genotype may offer some protection against the condition.

In this study, researchers found that the bioactive lipid sphingosine 1-phosphate and its receptor, S1PR3, are essential for regulating mechanical pain sensitivity in mice.

This study found that the wild-derived mouse strain Mus pahari has fragile skin that separates at subdermal levels under moderate force, potentially due to altered extracellular matrix development.

Skin lymphoproliferative disorders are hard to diagnose and often linked to systemic diseases, but most have a good prognosis with accurate diagnosis.

This article discusses the roles of pediatrics and dermatology departments at Yale University School of Medicine, but reports no specific clinical results.

This study in a nine-year-old boy from Lebanon identified a gene mutation (c.1066dup p.(Arg356Profs*16)) associated with a rare inborn error of immunity, characterized by craniosynostosis, jaundice, and several other symptoms, expanding the known genotypic and phenotypic spectrum of this condition.

This study found that the prevalence of polycystic ovary syndrome was 16.6% with Rotterdam criteria but decreased to 6.3% or 8.5% when using alternative criteria involving antral follicle count or anti-Müllerian hormone.

In this study, researchers found that the number of dermal papilla cells in hair follicles determines hair size and shape in mice, suggesting potential avenues for addressing hair loss.

This study found that women with androgenetic alopecia or alopecia areata have significantly lower serum ferritin levels than those without hair loss, suggesting a potential link between these types of alopecia and decreased iron stores.

This article reviews considerations and guidelines for testosterone therapy in older men with low testosterone levels but does not provide new clinical results, emphasizing the need for ongoing evaluation and careful management, particularly regarding risks related to prostate and cardiovascular health.

This study suggests that while hair analysis using GC-MS is a sensitive method for detecting cocaine ingestion, it may not reliably indicate the amount, timing, or duration of drug use due to interindividual variability and multiple incorporation mechanisms.

This study concluded that terminal Schwann cells are essential for the maintenance and regeneration of mechanosensory lanceolate complexes at hair follicles in adult mice.

This review discusses the multifactorial etiology of hypospadias, including genetic predispositions and possible environmental factors, and highlights the need for further studies on genetic and environmental contributions to its increasing prevalence, without presenting new findings.

This study found no direct relationship between low serum ferritin and chronic diffuse telogen hair loss in women, questioning the usefulness of serum ferritin measurement and iron supplementation for managing this condition.

This review offers transgender hormone treatment guidelines to assist healthcare providers in improving transgender patients' access to and outcomes of medical care, but it reports no new clinical results.

This study suggests that decreased SHBG levels and increased FAI, free testosterone, and DHEAS concentrations are effective in diagnosing PCOS in epidemiological studies of women of reproductive age.

This article discusses the controversy over serum ferritin levels in diagnosing iron deficiency in women with hair loss but reports no new findings, emphasizing the need for consistent reference ranges.

This study found that general practitioners' diagnostic accuracy for skin conditions aligned with histological diagnosis in 24% of cases, whereas dermatologists achieved 77% concordance.

This study found that careful light microscopy using fluid-mounted hair improves detection of the pili annulati phenotype, which varies widely in expression and affects hair fragility.

This study found that a genetic test using 5 to 20 SNPs can predict male pattern baldness with variable accuracy in European men, especially those aged 50 and older.

This review develops expert-guided recommendations for hidradenitis suppurativa management, highlighting evidence for the effectiveness of antibacterial and anti-tumor necrosis factor therapies, but reports no new clinical trial results.

This review explores the significant impacts of hormonal changes within normal physiological ranges and suggests examining low-dose effects from chemicals disrupting hormonal activity; it presents no new clinical results.

This article discusses how mechanical stress may contribute to the development of hidradenitis suppurativa lesions, drawing on historical research and highlighting the possible role of IL-17-mediated inflammation.

This study found that women with polycystic ovary syndrome in the UK show significant differences in phenotypic and metabolic characteristics based on ethnicity, age, and obesity, influencing management strategies.