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The document concludes that personalized hormonal treatments are important for transgender individuals and more research is needed for non-binary treatments.

Targeted anticancer therapies can cause severe side effects similar to traditional chemotherapy, but with different types.

There are various effective hormone treatments for puberty induction in boys and girls with hypogonadism, and starting treatment early is important.

Some drugs may help treat both COVID-19 and radiation injury.

Inorganic-based biomaterials can quickly stop bleeding and help wounds heal, but they may cause issues like sharp ion release and pH changes.

Autologous fat transfer improves hair growth in scarring alopecia and allows for denser hair transplants.

Current treatments for Alopecia Areata have mixed success, and there's a need for better, more accessible options and support for affected individuals.

Digital gangrene can be an initial symptom of late-onset systemic lupus erythematosus.

Digital gangrene can be a rare first sign of late-onset systemic lupus erythematosus.

Ciproterone acetate improves hair regrowth and acne in most female patients.

Many women who have used performance-enhancing drugs in Finland show high rates of mental health and substance use issues, and most have normal red blood cell counts.

Hormonal treatments can improve acne, but they come with potential side effects and risks.

Pregnancy causes skin changes like darkening, hair thickening, nail changes, and increased risk of skin growths, most of which usually resolve after birth.

Sex hormones affect reproduction, sexual development, and oral health, and it's important for dental practitioners to understand their effects and interactions.

Healthcare providers need better understanding and cultural sensitivity to improve care for transgender patients with kidney failure needing transplants.

Hormone treatment for transgender patients may not need to be stopped before surgery, but more research is needed, especially on estrogen.

Endocrine therapies for cancer significantly increase the risk of hair loss.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Skin diseases linked to insulin resistance should be managed to prevent diabetes and reduce heart disease risk.

The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

The conclusion is that managing cholesterol is important for women, especially during pregnancy, breastfeeding, and with PCOS, and involves regular screening and careful treatment choices.

Treating PCOS is complex, involving medication like metformin and lifestyle changes, and requires attention to mental health due to high depression and anxiety rates.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

Healthcare providers need better education and policies to serve transgender individuals effectively.

Cyproterone acetate with ethinyl estradiol is effective for treating skin symptoms related to high androgen levels, like in PCOS.

Progestogens are essential in menopausal hormone therapy to prevent uterine cancer and must be chosen carefully based on individual needs.