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Drugs penetrate scalp skin better than abdominal skin, with scalp hair follicles aiding in higher drug delivery.

Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.

Androgens play a role in female sexual function, and testosterone therapy can help women with low sexual desire, but more research is needed on treatments and long-term safety.

Finasteride works better than Permixon in reducing dihydrotestosterone levels.

Human hair follicles produce and respond to erythropoietin, helping protect against stress.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Women with PCOS often feel stigmatized and have mood issues, which can lower their sexual satisfaction, but proper treatment and support can help.

Natural 5AR inhibitors effectively improve mild to moderate hair loss in men.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

Plant extracts effectively reduce hair loss and increase growth, offering a safe alternative treatment.

Microneedle technology has improved drug delivery and patient comfort but needs more research for broader use.

Liraglutide caused significant weight loss in some obese women with PCOS, especially those with severe obesity and insulin resistance.

Nanocrystals improve skin penetration and stability of caffeine, suggesting a new method for delivering similar substances through the skin.

Minoxidil improves blood flow in heart failure patients.

Squalene-based carriers improve delivery of a treatment to hair follicles for alopecia areata.

Male pattern baldness is mostly inherited, involves many genes, and is linked to other traits like early puberty and strong bones.

Researchers found 15 new genetic links to skin traits in Japanese women.

Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.

Skin bacteria, specifically Staphylococcus aureus, help in wound healing and hair growth by using IL-1β signaling. Using antibiotics on skin wounds can slow down this natural healing process.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

Women with regular menstrual cycles and PCOS have linked kisspeptin and LH hormone patterns, unlike those with irregular cycles.

Shift nurses show altered body temperature and stress hormone levels, suggesting their body clocks adjust to irregular schedules.

The document concludes with guidance for doctors on diagnosing and treating hirsutism effectively and safely.