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Skin stem cells are maintained by signals from nearby cells and vary in their ability to renew and mature.

Skin spheroids with both outer and inner layers are key for regrowing skin patterns and hair.

LGR5 helps maintain corneal cell characteristics and prevents unwanted changes by controlling specific cell signaling pathways.

Injected human hair follicle cells can create new, small hair follicles in skin cultures.

Certain human skin cells marked by CD44 and ALDH are rich in stem cells capable of long-term skin renewal.

The "Two-Cell Assemblage" assay is a new, simple method to identify substances that may promote hair growth.

Hair follicle culture helps develop new treatments for hair loss.

The patch assay can create mature hair follicles from human cells and may help in hair loss treatments.

Conditioned media from human amniotic fluid-derived stem cells helps skin heal and protects against aging from sun exposure.

PlacMA hydrogels from human placenta are versatile and useful for cell culture and tissue engineering.

Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.

Changing how mesenchymal stromal cells are grown can improve their healing abilities.

Biomaterials combined with stem cells show promise for improving tissue repair and medical treatments.

Different stem cells have benefits and challenges for tissue repair, and more research is needed to find the best types for each use.

The document concludes that while some organisms can regenerate body parts, mammals generally cannot, and cancer progression is complex, involving mutations rather than a strict stem cell hierarchy.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.

Autophagy is important for human hair growth and health.

Using defensins to activate stem cells may improve skin aging signs without causing inflammation.

Concentrated nanofat helps mice grow hair by activating skin cells and may be used to treat hair loss.

Conditioned media from mesenchymal stem cells show promise for tissue repair and disease treatment, but more research is needed on their safety and effectiveness.

Blood stem cells are diverse, influenced by many factors, and understanding them is key for progress in regenerative medicine.

NIR-II imaging effectively tracked stem cells that helped repair facial nerve defects in rats.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

iPSCs could help develop treatments for hair loss.

Low oxygen conditions improve how well certain stem cells from embryos can make hair grow longer and faster.

Hair thinning causes stem cell loss through a process involving Piezo1, calcium, and TNF-α.

The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.

Stem cell therapy shows promise in improving burn wound healing.

New treatments for hair loss show promise, including plasma, stem cells, and hair-stimulating complexes, but more research is needed to fully understand them.