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The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Adult female acne is a complex condition that can worsen with menopause, requiring holistic treatment and tailored skincare at different life stages.

Some cancer and immune system drugs can cause serious side effects, including heart, lung, nerve, and organ damage, which need careful monitoring and management.

Acne can't be cured but can be managed with treatments like benzoyl peroxide and diet changes; it's costly and can lead to scarring and mental health issues.

Hormones during puberty increase certain receptors in the brain, and this change is influenced by estrogen levels.

Adult female acne is complex and requires a combination of treatments for effective management.

New drugs targeting DNA enzymes show promise for cancer treatment but have side effects like immune system suppression and hair loss.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

Finasteride, a drug used for certain conditions, can cause serious side effects like sexual dysfunction, suicidal thoughts, and increased diabetes risk, and there's a need for more awareness and research about these effects.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Progesterone and related compounds may help control seizures linked to the menstrual cycle but have limitations that need addressing.

Progesterone treatment improved seizures in a woman with menstrual cycle-related epilepsy, but a wrong medication worsened her condition.

Neuroimaging suggests that treatments targeting brain steroids could help control epilepsy, especially types linked to the menstrual cycle.

Mesenchymal stem cell-derived exosomes significantly increase hair density and thickness in androgenic alopecia patients.

Acne can be managed with various treatments and requires psychological support due to its emotional impact.

The document shows the state of pharmaceutical patents as of 1999, focusing on treatments for various diseases.

Finasteride treats hair loss but may cause low libido, erectile issues, and depression.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Targeting the skin's endocannabinoid system could help treat skin disorders.

Neurosteroids show promise for treating epilepsy and more research is needed.

PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.

Post-finasteride syndrome causes lasting sexual, neurological, and physical side effects in some people after taking finasteride.

Finasteride can cause sexual problems and depression in young men.

Neurosteroids can influence behavior by modulating brain inhibition, with potential for treating psychiatric disorders.

Menopausal acne is treated with medications and lifestyle changes, but careful choice is needed due to side effects.

Progesterone and its byproducts control a specific receptor in the brain independently of progesterone receptors, affecting conditions related to the menstrual cycle.