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Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

Removing Mediator 1 from certain mouse cells causes teeth to grow hair instead of enamel.

High-dose finasteride may help treat glioblastoma but needs localized delivery for effectiveness.

miR-31 regulates hair growth by controlling gene expression in hair follicles.

The KRTAP11-1 gene promoter is crucial for specific expression in sheep wool cortex.

The Bcl-2 protein is important for keeping hair follicle stem cells working and preventing hair loss.

High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.

Cold Atmospheric Microwave Plasma (CAMP) helps hair cells grow and could potentially treat hair loss.

The lentiviral array can monitor and predict gene activity during stem cell differentiation.

Removing integrin α3β1 from hair stem cells lowers skin tumor growth by affecting CCN2 protein levels.

Integrin alphavbeta6 is important for wound healing and hair growth, and blocking it may improve these processes.

Skin-derived precursors in hair follicles come from different origins but function similarly.

Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.

The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.

Mutations in the LSS gene cause a rare type of hereditary hair loss.

Disrupting Smad4 in mouse skin causes early hair follicle stem cell activity that leads to their eventual depletion.

The guide explains how to study human skin fat cells and their tissue, aiming to improve research and medical treatments.

A yeast-based test can detect the steroid methyltestosterone in urine longer than traditional methods.

Both human platelet lysate and minoxidil can promote hair growth, but they affect different genes and cell survival rates.

A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

The treatment was ineffective in humans.

The document concludes that the development of certain tumors is influenced by genetic background and that a specific gene modification can lead to tumor regression and reduced growth.

A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.

Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.

Wnt and Notch signaling help wound healing by promoting cell growth and regulating cell differentiation.

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.

The conclusion is that recognizing hair growth cycles can improve the precision of dietary and health assessments from hair analysis.

Light can turn on hair growth cells through a nerve path starting in the eyes.

Keratins are important for skin cell health and their problems can cause diseases.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.