10 citations
,
June 2024 in “Frontiers in Genetics” This study analyzed RNA-seq data from various animal breeds and suggested that similar molecular mechanisms may underlie wool fineness in different sheep breeds. Researchers identified 32 candidate genes related to hair follicle regulation, providing insights for molecular breeding and evolutionary studies.
7 citations
,
September 2019 in “European Journal of Case Reports in Internal Medicine” This case report describes a 68-year-old man who developed both alopecia areata and bullous pemphigoid after starting linagliptin for diabetes, suggesting a possible link with DPP-4 inhibitors.
4 citations
,
November 2021 in “Biomedicines” This review discusses the challenges in diagnosing primary cicatricial alopecias and explores how improved communication and digital pathology could enhance diagnosis, but it reports no new clinical results.
1 citations
,
January 2023 in “Dermatologic Therapy” This study reported that a single treatment using macrofocused ultrasound energy with a 2 mm transducer significantly reduced pore count, pore volume, and pore index in 34 Thai subjects with enlarged facial pores over a 6-month period, with no adverse events observed.
March 2026 in “Cosmetics” This study found that combining Alexandrite laser with iontophoresis of chymotrypsin and papain enzymes reduced the laser pulse requirements compared to laser alone for treating paradoxical hypertrichosis in women with facial hirsutism, suggesting potential clinical benefits in managing this condition.
488 citations
,
July 2021 in “Cell” This review discusses the development, lineages, functions, and roles of fibroblasts in fibrosis across four organs, highlighting their capabilities in tissue repair and contributions to fibrotic disorders when aberrantly activated, but it reports no new experimental findings.
247 citations
,
June 2021 in “Frontiers in Cell and Developmental Biology” This review discusses the role of lncRNA Xist in cell growth regulation and disease development, particularly cancer, and reports no new experimental results.
114 citations
,
January 2016 in “Current topics in developmental biology/Current Topics in Developmental Biology” This review discusses the diverse roles of Frizzled proteins in developmental and homeostatic processes and reports no new experimental findings.
105 citations
,
December 2017 in “Journal of Biological Engineering” This review discusses the challenges of skin graft acceptance and examines current strategies and alternatives for full-thickness skin replacement and repair, noting that immunological rejection remains a significant hurdle.
83 citations
,
January 1998 in “Journal of Investigative Dermatology” In this study using human cell cultures, type 1 5α-reductase was found to vary in both protein heterogeneity and expression levels across different types of skin cells.
54 citations
,
December 2011 in “American Journal Of Pathology” This study found that immune-mediated destruction of bulge stem cells is a key factor in the alopecia observed in AE mice, suggesting it as a model for studying primary cicatricial alopecias, particularly lichen planopilaris.
28 citations
,
April 2021 in “Biomedicines” This review evaluates in vitro hair follicle models, techniques, and challenges without reporting new clinical results, emphasizing their future potential in hair transplantation.
19 citations
,
July 2020 in “EBioMedicine” In this study, the researchers identified a variant in the CCHCR1 gene associated with an alopecia areata subtype characterized by impaired keratinization and autoimmune events.
8 citations
,
August 2023 in “Journal of Investigative Dermatology” This study reported that in a mouse tail wound model, the synthetic dual inhibitor corin accelerated wound closure by enhancing re-epithelialization, and further in vitro experiments demonstrated increased expression of genes promoting keratinocyte migration, suggesting its potential as a treatment for chronic wounds.
7 citations
,
October 2024 in “Cells” This review discusses the potential of platelet-rich plasma in regenerative medicine and aging-related diseases but notes that clinical efficacy remains unclear due to varying study results and preparation inconsistencies.
7 citations
,
August 2020 in “Current topics in medicinal chemistry” This review discusses emerging cancer treatment methods focusing on cellular mechanisms unique to cancer cells and concludes no new clinical results.
6 citations
,
November 2023 in “Stem Cell Reports” In this discussion, the authors highlight the murine cornea as a powerful model for stem cell research, revealing new insights into stem cell properties, differentiation flexibility, and the importance of the stem cell niche, with potential implications for understanding various tissues, diseases, and therapies.
5 citations
,
September 2023 in “Molecules” This review examines physical methods like electron paramagnetic resonance spectroscopy, Raman spectroscopy, and differential scanning calorimetry, highlighting their complementary capabilities in analyzing biomolecular structures and mycobacterial interactions with reactive oxygen species and antioxidants.
5 citations
,
February 2022 in “Biophysical journal” This study developed a mathematical model indicating that the amino acid sequences of intermediate filament proteins, rather than flexibility differences, significantly impact assembly rates.
3 citations
,
April 2023 in “Veterinary sciences” This study found that among Large White × Min pigs, 15 significant copy number variation regions were associated with villi hair traits, and identified candidate genes potentially linked to cold resistance, suggesting implications for breeding cold-resistant pigs.
3 citations
,
January 2021 This chapter explains the mechanisms of facial aging and evaluates non-surgical treatments like thread lifts, platelet concentrates, high intensity focused ultrasound, and radio frequency for addressing aging signs, highlighting their potential for excellent patient outcomes.
2 citations
,
November 2025 in “Healthcare” This study found that among young patients with acne vulgaris, combining a 675 nm red-light laser with isotretinoin led to more rapid and pronounced improvement in lesion severity compared to laser treatment alone, without adverse events.
2 citations
,
November 2023 in “Biomolecules” This review article analyzes the role of the WNT signaling pathway in skin development, wound healing, and mechanical stretching, emphasizing its importance in understanding and potentially advancing treatments for skin-related diseases.
1 citations
,
July 2024 in “International Journal of Molecular Sciences” In this review, researchers introduced clinically tunable siRNA delivery systems for hair loss treatment, discussing design principles and analyzing relevant clinical trials to propose a framework for optimizing siRNA delivery in a clinical context.
1 citations
,
January 2024 in “Cellular & Molecular Biology Letters” This review evaluated the potential of adipose-derived stem cells (ADSCs) for burn treatment, finding promising regenerative healing effects, though most findings are at early experimental stages primarily in animal models.
1 citations
,
May 2022 in “International journal of molecular sciences” This study found that in Hutchinson–Gilford progeria syndrome, iPSCs committed to the keratinocyte lineage faster than normal cells, with LEF1 expression reduced and a partial rescue of the phenotype achieved through adenine base editing.
May 2026 in “The EMBO Journal” This study demonstrated how cellular flows and tissue mechanics guide the topological transformations in avian skin, essential for feather follicle development from scales.
April 2026 in “International Journal of Molecular Sciences” In this study, Ageratum houstonianum ethanolic extract and its active component agerarin were found to promote hair growth and follicle elongation by increasing SCUBE3 expression via activation of MAPK–AP-1 signaling in human dermal papilla cells, suggesting potential therapeutic value for treating hair loss.
January 2026 in “Pharmaceutics” This review discusses the dual role of extracellular vesicles in Alzheimer's disease, highlighting their potential in both exacerbating and alleviating the condition, and emphasizes the need for advanced technologies to enhance diagnosis and treatment.
November 2025 in “International Journal of Molecular Sciences” This review covers the diverse clinical applications of platelet-rich plasma in regenerative medicine but provides no new clinical results.