28 citations
,
September 2015 in “Wiener Klinische Wochenschrift” New skin substitutes for treating severe burns and chronic wounds are being developed, but a permanent solution for deep wounds is not yet available commercially.
19 citations
,
February 2017 in “Journal of radiation research” This study found that high-dose radiation can induce accelerated cellular senescence, inflammation, and loss of epithelial stem cells in mouse and human skin, contributing to radiation dermatitis.
9 citations
,
January 2021 in “RSC Advances” Non-thermal plasma helps hair grow by improving the area around hair follicles.
This study utilized a mouse model of traumatic brain injury to reveal that acute neurotrauma triggers widespread lipid metabolism reprogramming and storage lipid accumulation in microglial and monocyte populations, leading to lysosomal dysfunction, inhibited autophagy, and exacerbated inflammation through a pathological feedback loop.
15 citations
,
January 2019 in “Mediators of inflammation” This study concluded that Aloe vera fermentation significantly accelerates burn injury healing in rats by reducing inflammation and altering gut microbiota composition.
32 citations
,
February 2019 in “Journal of neurochemistry” This study found that pharmacological inhibition of sex steroid synthesis impacts pathogenic processes in traumatic brain injury in a sex-specific manner, with distinct effects of letrozole and finasteride on molecular and neurological outcomes.
January 2026 in “Food Science and Human Wellness” This research examined krill oil's effects on benign prostatic hyperplasia and found that it inhibited the growth of prostate cells in vitro and reduced prostate size and weight in a BPH rat model, suggesting potential as a prophylactic or therapeutic agent for BPH.
15 citations
,
March 2012 in “International journal of nanomedicine” In this study, local injection of nanosized recombinant human erythropoietin at the injury site improved skin regeneration and re-epithelialization in a mouse model of deep second-degree burns through coexpression of specific receptors.
24 citations
,
May 2021 in “Nature Communications” In this study, a dual recombinase-mediated genetic system showed that cavity macrophages accumulate on the surface of visceral organs during lung and liver injury but do not penetrate or contribute to tissue repair.
27 citations
,
August 2014 in “Journal of Cosmetic and Laser Therapy” This study compared the microscopic treatment zones created by different fractional lasers and radiofrequency in swine skin, finding distinct patterns and damage levels for each technology.
January 2015 in “Springer eBooks” Hair damage shows as fragility, dullness, and discoloration, varies by ethnicity, and is worsened by cosmetic procedures and diseases.
195 citations
,
January 2008 in “Photochemistry and Photobiology” This review discusses the effects of visible light on human skin, highlighting its role in pigmentation, thermal damage, and the treatment of several skin conditions, while noting limited sunscreen protection against it; no new clinical results are reported.
15 citations
,
July 2019 in “Lasers in surgery and medicine” This study found that 1,540 nm fractional erbium-glass laser treatment combined with topical minoxidil significantly increased hair regrowth in alopecia areata patches compared to minoxidil alone, with response rates of 60% versus 16%, though the long-term effects remain unknown.
15 citations
,
January 1996 in “Lasers in Surgery and Medicine” This letter discusses the state of laser hair transplantation as of its 1996 publication but reports no new findings or clinical results.
July 2026 in “Preprints.org” In this case study, a comprehensive reconstruction approach using autologous fat grafting, follicular unit excision hair transplantation, and scalp micropigmentation led to significant aesthetic and psychosocial improvements in a male patient with severe facial and scalp burn injuries.
265 citations
,
July 2012 in “Cell” This study found multipotent progenitors in sweat ducts that become unipotent after sweat gland development, highlighting distinct regenerative capabilities in adult glandular skin stem cell populations.
9 citations
,
July 2014 in “Facial Plastic Surgery” The authors find the endoscopic forehead midface lift to be a reliable and safe method for facial rejuvenation.
7 citations
,
April 2018 in “Facial Plastic Surgery” This source discusses the safety and effectiveness of the endoscopic brow lift as a well-established procedure for rejuvenating the upper third of the face, detailing surgical techniques, patient selection, and ways to minimize complications.
5 citations
,
April 2019 in “Plastic and reconstructive surgery. Global open” This literature review suggests that fractional laser therapies may positively impact hair regrowth in androgenic alopecia, though current evidence is mostly limited to small studies and case reports, highlighting a need for more comprehensive randomized controlled trials to confirm their efficacy and safety.
3 citations
,
July 2025 in “International Journal of Biological Sciences” This review highlights that the RNA modification N6-methyladenosine (m6A) plays a crucial role in regulating wound healing and tissue remodeling, with dysregulation contributing to complications in chronic wounds, such as diabetic ulcers and burn injuries, through mechanisms like impaired angiogenesis and increased oxidative stress.
January 2012 in “Methods in pharmacology and toxicology” This review discusses the expanding understanding of TRPV3's role in pain and skin pathology, while highlighting the need for further pharmacological research to fully resolve its functions.
August 2016 in “InTech eBooks” This source highlights the diverse scope of facial plastic and reconstructive surgery, noting the specialty's adaptability to changing trends and ethnic preferences for aesthetic outcomes, without reporting specific study results.
54 citations
,
September 2000 in “Archives of dermatology” In this study, 95% of respondents reported severe hair breakage or loss after using the Rio Hair Naturalizer System, with many experiencing significant and lasting hair loss.
38 citations
,
December 2019 in “Iranian Biomedical Journal” This study found that hair follicle stem cells could enhance burn wound healing and improve tissue tensile strength in rats.
28 citations
,
March 2017 in “Scientific Reports” This study found that minoxidil may protect against chemotherapy-induced peripheral neuropathy and potentially support hair recovery and tumor suppression in mouse models.
23 citations
,
April 1999 in “Dermatologic Clinics” This study found that the Epilight multiple wavelength pulsed-intense light source was effective for long-lasting hair removal, particularly in individuals with dark hair and light skin.
20 citations
,
March 2013 in “Journal of Lipid Research” This study examined the structural and biochemical mechanisms of human lipocalin prostaglandin D synthase, detailing substrate and product binding processes at the catalytic site and suggesting potential for drug delivery targeting hydrophobic molecules.
9 citations
,
January 2017 in “Elsevier eBooks” This chapter discusses the skin stem cell niche as a complex ecosystem and highlights the diverse components and interactions that influence stem cell function, but it reports no new experimental results.
1 citations
,
September 2025 in “Physiologia” This study found that systemic ovalbumin–aluminum sensitization followed by cutaneous challenge in mice induced thermal hyperalgesia, increased spinal cord gliosis, and sprouting of nociceptive fibers, along with elevated mast cell and nerve profile densities in the skin compared to controls.
1 citations
,
January 2025 in “BIO Integration” This review highlights that the combination of ultrasound and microneedles can enhance transdermal drug delivery by using physical and energy-driven mechanisms to improve drug penetration into deeper skin layers, with implications for precision medicine and chronic disease treatments.