research Function of KLF4 in Stem Cell Biology
KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.
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research 5α-Reductase Inhibitors: Progress and Therapeutic Potential
5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.
research Transient Stimulation of TRPV4-Expressing Keratinocytes Promotes Hair Follicle Regeneration in Mice
Activating TRPV4 in skin cells helps regrow hair in mice, possibly offering a treatment for hair loss.
research Identification of Differentially Expressed Genes in Actinic Keratosis Samples Treated with Ingenol Mebutate Gel
Ingenol mebutate gel changes gene expression related to skin development and immune response in actinic keratosis.
research Immune Privilege and Alopecia Areata
Restoring immune privilege in hair follicles could help treat certain types of hair loss.
research PBX1-SIRT1 Positive Feedback Loop Attenuates ROS-Mediated HF-MSC Senescence and Apoptosis
PBX1 reduces aging and cell death in stem cells by boosting SIRT1 and lowering PARP1.
research Phytochemistry and Pharmacological Studies of Glycyrrhiza Glabra: A Medicinal Plant Review
Licorice has many health benefits but more research is needed to fully understand them.
research Hairless-Knockout Piglets Generated Using CRISPR/Cas9 Exhibit Abnormalities in Skin and Thymus
Pigs without the Hairless gene showed skin and thymus changes, useful for studying human hair disorders.
research Hair Growth Promoting Activity of Discarded Biocomposite Keratin Extract
Keratin extract from human hair was found to promote hair growth in mice.
research Steroid Hormones: Overview and Medical Applications
Steroid hormones are crucial for body functions and have various medical uses, but their misuse can lead to dependence.
research Analysis of Phytochemistry and Antimicrobial Activity of Tridax Procumbens Linn
Tridax procumbens plant extracts, especially from ethanol, have strong antibacterial effects and contain beneficial compounds like flavonoids and tannins.
research Isolation and Characterization of Recombinant Murine Wnt3a
Scientists successfully purified a protein called Wnt3a, which is involved in processes like hair growth, but the overall yield was low, suggesting more work is needed to improve this.
research Topical Spironolactone in the Treatment of Ocular Graft-Versus-Host Disease
Topical spironolactone may help treat ocular graft-versus-host disease with minimal side effects.
research Androgen Receptor Ligands: Agonists and Antagonists
Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.
research Adipose-Derived Stem/Stromal Cells in Regenerative Medicine
Fat tissue stem cells show promise for repairing different body tissues and are being tested in clinical trials.
research NF-κB in Biology and Targeted Therapy: New Insights and Translational Implications
NF-κB signaling is crucial in many diseases and can be targeted for new treatments.
research Nanoemulgel as an Innovative Platform for Phytomolecules
Nanoemulgel improves delivery and effectiveness of plant-based drugs for various conditions.
research The Coenzyme A Precursor Pantethine Enhances Antitumor Immunity in Sarcoma
Pantethine may boost the immune system's ability to fight sarcoma.
research Ozone and Procaine Increase Secretion of Platelet-Derived Factors in Platelet-Rich Plasma
Ozone and procaine boost the release of healing factors in platelet-rich plasma.
research Cosmeceuticals: The Bioactive Elements in New-Age Beauty Products
Cosmeceuticals are popular for their skin health benefits and anti-aging effects.
research Novel Effect of Hyaluronan and Proteoglycan Link Protein 1 (HAPLN1) on Hair Follicle Cells Proliferation and Hair Growth
HAPLN1 can promote hair growth and may help treat hair loss.
research Metabolic Regulation of Stem Cells in Aging
Eating less can improve stem cell function and increase lifespan.
research Review of the Use of Platelet-Rich Plasma in the Treatment of Alopecia
PRP therapy might help increase hair growth for nonscarring alopecia, but more research is needed to confirm its effectiveness.
research Alopecia Areata: Genetic and Immunological Insights
Understanding the immune-related causes of Alopecia Areata has led to potential treatments like JAK inhibitors.
research Probing Androgen Receptor Co-Factor Selectivity Profiles: A Chemical Tool to Determine Cross-Talk Between Androgen Receptor and Beta-Catenin In Vivo
PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.
research Primary Cicatricial Alopecias
The document concludes that early diagnosis and treatment are crucial for managing rare hair loss disorders and that more research is needed to improve treatment strategies.
research Male Androgenetic Alopecia
Male androgenetic alopecia involves hair follicle miniaturization due to DHT, with potential treatments using inhibitors and blockers.
research The Relationship Between Keratin 18 and Epithelial-Derived Tumors: As a Diagnostic Marker, Prognostic Marker, and Its Role in Tumorigenesis
Keratin 18 helps diagnose and predict cancer progression and affects cancer growth and spread.
research Development and Characterization of Film Forming Spray of 5% Minoxidil for Baldness Due to Androgenetic Alopecia
This study explores a film-forming spray with 5% minoxidil for treating androgenetic alopecia, aiming to reduce side effects like dry scalp and irritation associated with traditional formulations. The spray forms a thin, non-sticky film that enhances drug contact time and permeability, leading to continuous release and improved patient comfort. The formulation was evaluated for pH, viscosity, spray angle, and drug content, with formulation F2 (1.8% hydroxypropyl methylcellulose E15) showing promising results. The study concludes that this novel delivery system could effectively treat patchy hair loss or baldness in men with androgenetic alopecia, improving therapeutic outcomes and patient compliance.
research Dissolvable Microneedles Loaded with Ginsenoside Rg3 Liposome: A Transdermal Delivery Approach for Alopecia Treatment
Dissolvable microneedles with Ginsenoside Rg3 can help treat hair loss by improving drug delivery and stimulating hair growth.