54 citations,
January 2023 in “Signal Transduction and Targeted Therapy” New therapies are being developed that target integrin pathways to treat various diseases.
46 citations,
October 2018 in “JCI insight” CD8+ T cells are involved in alopecia areata and may cause disease relapse.
29 citations,
June 2015 in “Kidney International” Disrupting the Flcn gene in mice causes early kidney cysts and tumors, which can be treated with rapamycin.
16 citations,
November 2021 in “Antioxidants” Managing oxidative stress might help treat low testosterone and related chronic diseases in aging men.
8 citations,
May 2019 in “Journal of Stem Cells & Regenerative Medicine” Dental pulp stem cells are better for tissue repair, while fat tissue stem cells may be more suited for wound healing and hair growth.
6 citations,
December 2022 in “Frontiers in Pharmacology” Quercetin may help improve symptoms of polycystic ovary syndrome.
6 citations,
January 2015 in “Journal of regenerative medicine & tissue engineering” The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.
3 citations,
January 2020 in “PubMed” Adding insulin-like growth factor 1 and bone marrow-derived stem cells to a collagen-chitosan scaffold helps wounds heal faster and regrows hair follicles.
March 2024 in “Cosmetics” New regenerative techniques show promise for improving skin, healing wounds, and growing hair.
December 2023 in “International journal of molecular sciences” Chromosomal differences affect how muscle cells respond to testosterone.
November 2023 in “ACS Omega” New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.
May 2023 in “International Journal of Molecular Sciences” Mesenchymal stem cells could help treat radiation-induced bladder damage but more research is needed to overcome current limitations.
May 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Loss of TET2 increases the risk of skin and oral cancer.
April 2022 in “Medicina estética” Minoxidil is the only FDA-approved treatment for female hair loss, with other potential treatments needing more research for effectiveness.
The book provides a guide to cosmetic surgery for people with darker skin, covering various treatments and addressing their unique skin characteristics.
854 citations,
February 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Understanding hair follicle development can help treat hair loss, skin regeneration, and certain skin cancers.
365 citations,
November 2018 in “Journal of Allergy and Clinical Immunology” People with atopic dermatitis have different skin bacteria, and targeting these bacteria might help treat the condition.
293 citations,
November 2005 in “Trends in Immunology” Stress can worsen skin conditions and stop hair growth by affecting the body's stress response system.
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September 2012 in “Gastroenterology” Colorectal cancer development involves both genetic changes and epigenetic alterations like DNA methylation and microRNA changes.
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July 2014 in “Proceedings of the National Academy of Sciences of the United States of America” FGF5 gene mutations cause unusually long eyelashes by affecting hair growth regulation.
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October 2017 in “Advanced drug delivery reviews” The review suggests that there are various treatments to help restore skin color after severe burns.
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December 2015 in “International Journal of Molecular Sciences” Melanocyte stem cells are crucial for skin pigmentation and have potential in disease modeling and regenerative medicine.
32 citations,
July 2017 in “Molecular diagnosis & therapy” MicroRNA-21 could help diagnose and treat skin fibrosis.
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February 2017 in “Molecular Medicine Reports” Activating Notch signaling can kill basal cell carcinoma cells.
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November 2015 in “Oxidative Medicine and Cellular Longevity” Fibroblast Growth Factor-9 helps repair heart damage after a heart attack by creating new blood vessels, especially in diabetics.
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February 2019 in “Journal of Cellular and Molecular Medicine” Researchers created a rat model to study skin damage caused by radiation, which could help develop new treatments.
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August 2023 in “Advanced Science” Nitric Oxide has potential in medicine, especially for infections and heart treatments, but its short life and delivery challenges limit its use.
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July 2022 in “Journal of Medicinal Chemistry” Adding a second method to PROTACs could improve cancer treatment.
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April 2022 in “Biomedicine & pharmacotherapy” Using three different drugs together may better treat eye diseases like glaucoma and macular degeneration.
5 citations,
October 2021 in “Frontiers in Cell and Developmental Biology” Fat tissue under the skin affects hair growth and aging; reducing its inflammation may help treat hair loss.