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Treating psoriasis on the scalp, nails, and skin folds is challenging, often requiring systemic treatments for severe cases, with some success in topical and biologic treatments.

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.

Platelet-rich plasma might help tissue regeneration in dentistry, but results vary and more research is needed.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.

Antioxidants may help fight oxidative stress linked to autoimmune skin diseases.

Niosomes are promising for skin drug delivery, offering benefits like improved drug penetration and stability.

Acne is a chronic disease linked to various systemic conditions and has significant psychological and social effects.

Some plant-based treatments can help with benign prostatic hyperplasia symptoms, but more research is needed to confirm their safety and effectiveness.

Some systemic treatments work for nail psoriasis but can have serious side effects.

Neurosteroids show promise for treating epilepsy and more research is needed.

Wound healing insights can improve regenerative medicine.

Lamins are vital for cell survival, organ development, and preventing premature aging.

Topical JAK inhibitors may help treat some skin conditions but need more research.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

Some breast cancer patients still experience hair loss three years after chemotherapy, especially with taxane-based treatments.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

FOXN1 gene variants cause low T cells and immune issues from birth.

Scalp cooling significantly reduces hair loss in chemotherapy patients.

Certain drugs that block specific enzymes can help treat prostate diseases.

Wounds on the face usually heal with scars, but understanding how some wounds heal without scars could lead to better treatments.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

CYLD mutations cause a variety of skin tumors with symptoms starting around age 16, and treatments are currently limited.

A blood pressure drug, diltiazem, may also help treat influenza.

Different types of hair loss in lupus need careful diagnosis for proper treatment.

Two patients with porphyria cutanea tarda experienced their grey hair turning dark again.

Hair loss requires customized treatments based on its various causes and types.

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

Human hair has a protective lipid layer that can be damaged by moisture and treatments, affecting hair growth and health.

New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.