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Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.

The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.

Finasteride helps reduce heart issues and improves heart function.

Cancer treatments often cause hair disorders, significantly affecting patients' quality of life, and better management methods are needed.

Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.

Scalp cooling can help prevent chemotherapy-induced hair loss with a 50-90% success rate and is safe for patients.

Bimatoprost is promising for treating some types of hair loss but needs more testing for androgenetic alopecia.

Tofacitinib citrate is effective for moderate-to-severe chronic plaque psoriasis but has safety concerns at higher doses.

The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.

Infertile men are more likely to produce sperm with abnormal chromosome numbers, which can affect pregnancy success and embryo health.

Many skin patients also have mental health issues, and doctors should treat both together.

Interferons are effective for some skin conditions and cancers, but can have side effects and need more research for optimal use.

Modified stem cells from umbilical cord blood can make hair grow faster.

Anti-cancer treatments can cause reversible hair loss, skin sensitivity, pigmentation changes, nail damage, and skin reactions, with a need for more research on managing these side effects.

Scientists created keratinocyte cell lines from human hair that can differentiate similarly to normal skin cells, offering a new way to study skin biology and diseases.

The document concludes that more research is needed to understand and treat Beard Alopecia Areata due to limited current knowledge and evidence.

The new chemotherapy combination of WP 631 and Epothilone B shows enhanced effectiveness against ovarian cancer but requires more research on its safety.

Negative expectations can cause adverse effects in dermatology treatments, like with finasteride for baldness, and careful communication can help reduce these nocebo responses.

New protein changes may be involved in the immune attack on hair follicles in alopecia areata.

Modified KGF mRNA helps skin cells grow and move faster, which may improve wound healing.

Clascoterone is a new, effective, and safe acne treatment without systemic side effects.

Antiandrogens are the main treatment for hirsutism, with individualized care and safe, affordable options needed.

Hair and scalp pain is more common and severe in breast cancer patients on chemotherapy than those on tamoxifen.

Retinoids and narrowband UVB phototherapy are effective for treating psoriasis and can reduce treatment time when used together.

Adding platelet-rich plasma improves hair density and thickness in androgenetic alopecia.

The mTOR pathway proteins are altered in the hair follicles of patients with Lichen Planopilaris and Frontal Fibrosing Alopecia.

The document concludes that individualized treatment for malignant epithelial tumors is necessary and more research on metastatic squamous cell carcinoma treatments is needed.