9 citations
,
December 2020 in “Dermatologic Therapy” This review found that oral and topical phosphodiesterase inhibitors and topical prostaglandin analogues are safe and effective treatments for various skin diseases, including psoriasis, atopic dermatitis, vitiligo, and alopecia.
9 citations
,
November 2020 in “Medical Hypotheses” Hair loss may link to weaker COVID-19 immunity, suggesting possible need for extra vaccine boost.
9 citations
,
July 2018 in “Current Pharmaceutical Design” This review discusses the importance of heme oxygenase in skin physiology and disease, but it reports no new clinical results; the authors highlight its potential as a treatment target for conditions like atopic dermatitis and psoriasis.
9 citations
,
September 2017 in “Nanoscale Research Letters” This study found that combining TIMP-1 with graphene oxide promoted skin tissue regeneration in rats and provided sustained release of TIMP-1 over 40 days.
9 citations
,
May 2005 in “Expert Review of Clinical Immunology” This article examines anticytokine therapies for autoimmune diseases, highlighting the potential of anti-interferon-γ as a universal treatment for certain conditions and noting varying effectiveness of tumor necrosis factor-α inhibitors.
8 citations
,
April 2020 in “Journal of Ethnopharmacology” This review assessed experimental studies on herbs used for alopecia, identifying potential mechanisms involving hair cycle management and keratinocyte processes, but highlighted a need for improved evidence on quality control and toxicity of these herbal treatments.
8 citations
,
June 2019 in “Scientific Reports” This study found that the retinoid receptor and PPAR pathway are involved in hair follicle miniaturization in androgenetic alopecia, alongside androgen receptors.
8 citations
,
May 2017 in “Chinese Journal of Integrative Medicine” Among in vitro and in vivo models, this study found that Miscanthus sinensis var. purpurascens flower extract may promote hair growth, potentially by modulating growth factor expressions and facilitating earlier hair follicle transitions in treated mice.
8 citations
,
May 2017 in “Current traditional medicine” This review explores the phytochemistry and phytopharmacology of Urtica dioica but reports no new experimental findings, focusing on its traditional uses and range of bioactive constituents.
8 citations
,
March 2014 in “American Journal of Pathology” This study found that hairless mice with homozygous mutations developed significantly more aggressive basal cell carcinomas and a heightened inflammatory response to UVB exposure compared to their haired littermates.
8 citations
,
August 1997 in “Australasian Journal of Dermatology” This review discusses the distinctive non-infective skin presentations of HIV infection from a dermatological perspective and reports no new clinical findings.
8 citations
,
February 1997 in “International journal of environmental analytical chemistry” This study determined that most elemental concentrations in Mexican medicinal plants were similar to agricultural products, with bromine being an exception.
7 citations
,
March 2025 in “Archives of Dermatological Research” This study found that trichoscopy is essential for evaluating the severity of alopecia areata and predicting treatment responses, contributing to more personalized patient management.
7 citations
,
October 2024 in “Frontiers in Immunology” In this study, researchers prepared a humanized CXCL12 antibody for alopecia areata treatment, finding it significantly delayed disease onset in mice and reduced immune cell activation, suggesting potential as an immune modulatory therapy.
7 citations
,
September 2024 in “Applied Microbiology and Biotechnology” In this study, researchers observed that Malassezia species show different lipid metabolism and growth patterns depending on pH, with slightly acidic conditions promoting beneficial lipid bio-conversion for skin health, while neutral pH resulted in lower growth and lipid content, potentially negatively impacting the skin.
7 citations
,
April 2023 in “Frontiers in immunology” This source reports that a network meta-analysis found oral baricitinib and ruxolitinib to be effective and safe for treating alopecia areata, significantly improving response rates over placebos and showing fewer adverse effects than steroid treatments, though precise dosing needs further study.
7 citations
,
January 2019 in “Pharmaceutical Biology” This study suggests that Eclipta prostrata may promote hair growth in mice and human dermal papilla cells through regulating FGF-7 and mTOR signaling.
7 citations
,
January 2018 in “Medicinski arhiv” In this study, a herbal extract mixture significantly reduced IL-1α gene expression in HaCaT cells, suggesting it may aid in the treatment of nonscarring alopecia.
7 citations
,
October 2013 in “British Journal of Dermatology” This article describes how HIV-related skin disorders vary in presentation among pigmented skin types and highlights challenges in their diagnosis due to atypical disease manifestations.
7 citations
,
April 2012 in “Biomolecular concepts” This article reviews the role of keratins in epithelial function and structure, discussing their involvement in growth control, organelle functions, and pathomechanisms of disorders, but reports no new clinical results.
7 citations
,
March 2012 in “European Journal of Pediatrics” This case report describes a 4.5-year-old boy with steroid-resistant nephrotic syndrome linked to X-linked recessive ichthyosis, where remission was achieved using cyclosporine, suggesting STS deficiency as a potential genetic cause of the condition.
7 citations
,
January 2011 in “Veterinary Pathology” In this case report, a 9-year-old horse was diagnosed with alopecia areata contributing to Malassezia dermatitis, involving lymphocyte infiltration and symptoms consistent with yeast presence.
7 citations
,
May 2010 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” This preliminary study observed that melanoblasts are preserved in the white hair follicles of segmental vitiligo lesions.
6 citations
,
January 2022 in “GSC Biological and Pharmaceutical Sciences” This review discusses the ethnobotanical use and bioactivity of Eclipta prostrata, highlighting its potential in treating various conditions and linking its effects to secondary metabolites.
6 citations
,
March 2021 in “Cytotechnology” This review examines recent findings on COVID-19 pneumonia treatment using mesenchymal stem cells and reports no new clinical results; the authors highlight MSCs' potential due to their immunomodulatory and tissue-regenerative properties.
6 citations
,
August 2020 in “Dermatology and Therapy” This study found that patients with alopecia areata had significantly lower serum vitamin D levels and higher odds of vitamin D deficiency, but no significant difference in serum calcium levels, compared to controls.
6 citations
,
February 2019 in “Scientific reports” This study demonstrated that allopregnanolone administration caused significant scratching in atopic dermatitis mice, and ethanol-induced scratching may be linked to increased brain allopregnanolone levels.
6 citations
,
August 2017 in “Physiological Research” This study suggests that setipiprant's inhibitory effect on aldose reductase may contribute to its anti-inflammatory properties, adding a possible mechanism beyond its known action on the prostaglandin D2 receptor.
6 citations
,
October 2016 in “Journal of Chemotherapy” This case report describes a rare instance of alopecia universalis occurring eight weeks after discontinuing pegylated interferon α and ribavirin therapy, highlighting the need for awareness among healthcare providers.
6 citations
,
January 2016 in “Dermatology Review” This review discusses the role of various stem cell niches in the skin and their potential application in treating skin diseases, but reports no new clinical results.