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Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

Hair follicle development and microbes help regulatory T cells gather in newborn skin.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

Antibiotics can reduce acne but may lead to resistant bacteria, and understanding the skin's bacteria is important for treatment.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Silver nanoparticles coated with substances like PEG showed strong antibacterial effects and improved wound healing when used in hydrogels.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Probiotic bacteria improved skin and hair health in aged mice.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Rhodococcus equi causes severe pneumonia in young foals, and effective vaccines are needed due to foals' weak immune responses.

Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.

The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

Targeting the skin's endocannabinoid system could help treat skin disorders.

Zinc deficiency in children can cause skin issues and can be serious if not diagnosed and treated properly.

Both vitiligo and alopecia areata involve an immune response triggered by stress and specific genes, with treatments targeting this pathway showing potential.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.

Topical JAK inhibitors may help treat some skin conditions but need more research.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Immunosuppressive and anti-TNF therapies in IBD patients can increase the risk of skin cancer and cause various skin issues.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

Ginseng and its compounds may help hair growth and prevent hair loss, but more human trials are needed to confirm this.

Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.

Changes in skin microbes play a role in some skin diseases and could lead to new treatments.