research The Influence of Interferon on Healthy and Diseased Skin
Type I interferons play a key role in the development of various skin diseases.
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research Regulatory T Cells Are Required for Normal and Activin-Promoted Wound Repair in Mice
Regulatory T cells are essential for normal and improved wound healing in mice.
research The Function and Structure of the Skin
The skin protects the body, regulates temperature, senses touch, and makes vitamin D.
research Bacteria Induce Skin Regeneration
Certain bacteria can enhance skin regeneration.
research Alopecia Areata: A Review of Disease Pathogenesis
Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.
research Dupilumab: A Review of Present Indications and Off-Label Uses
Dupilumab is being tested for many new skin, respiratory, and gastrointestinal conditions.
research Xenobiotic-Metabolizing Enzymes in the Skin of Rat, Mouse, Pig, Guinea Pig, Man, and in Human Skin Models
Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
research Thyroid Diseases and Skin Autoimmunity
Thyroid diseases may contribute to autoimmune skin diseases, and more research is needed on their relationship.
research Icariin Promotes Mouse Hair Follicle Growth by Increasing Insulin-Like Growth Factor 1 Expression in Dermal Papillary Cells
Icariin helps mouse hair grow by boosting a growth factor in skin cells.
research IL-12/IL-23 Neutralization Is Ineffective for Alopecia Areata in Mice and Humans
Blocking IL-12/IL-23 does not help with hair loss in alopecia areata for mice or humans.
research Flightless I Exacerbation of Inflammatory Responses Contributes to Increased Colonic Damage in a Mouse Model of Dextran Sulfate Sodium-Induced Ulcerative Colitis
High levels of the protein Flightless I worsen ulcerative colitis symptoms in mice.
research Modulation of Macrophage Functions by ECM-Inspired Wound Dressings – A Promising Therapeutic Approach for Chronic Wounds
ECM-inspired wound dressings can help heal chronic wounds by controlling macrophage activity.
research Immune-Mediated Skin Reactions Induced by Recombinant Antibodies and Other TNF-Alpha Inhibitors
TNF-alpha inhibitors can cause various immune-related skin issues.
research The Alopecia Areata Phenotype Is Induced by the Water Avoidance Stress Test in CCHCR1-Deficient Mice
Stress can cause a type of hair loss in mice lacking the CCHCR1 gene.
research Abstracts
New treatments and diagnostic methods for various animal skin conditions showed promising results.
research Impact of Diet and Dietary Supplements on Acne Vulgaris
Diet and supplements can significantly affect acne, with some foods and nutrients reducing and others worsening it.
research Phosphodiesterase (PDE) Inhibitors for the Treatment of Inflammatory Skin Conditions
PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.
research Severe Cutaneous Adverse Reactions to Drugs
Some drugs can cause rare but potentially deadly skin reactions, and early treatment and avoiding the drug again are key.
research JAK Inhibitors: New Players in the Field of Immune-Mediated Diseases Beyond Rheumatoid Arthritis
JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.
research Acne, the Skin Microbiome, and Antibiotic Treatment
Antibiotics can reduce acne but may lead to resistant bacteria, and understanding the skin's bacteria is important for treatment.
research Short-Chain Fatty Acids from Cutibacterium Acnes Activate Both a Canonical and Epigenetic Inflammatory Response in Human Sebocytes
Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.
research Topical Janus Kinase Inhibitors: A Review of Applications in Dermatology
Topical JAK inhibitors may help treat some skin conditions but need more research.
research Review Article: Dermatological Complications of Immunosuppressive and Anti-TNF Therapy in Inflammatory Bowel Disease
Immunosuppressive and anti-TNF therapies in IBD patients can increase the risk of skin cancer and cause various skin issues.
research A Review on Traditional Uses, Phytochemistry, and Pharmacology of Eclipta Prostrata (L.) L.
Eclipta prostrata has many traditional uses and health benefits, but more research is needed to understand how it works and ensure it's safe.
research Baricitinib: From Rheumatoid Arthritis to COVID-19
Baricitinib helps treat several diseases, including COVID-19, but has side effects and needs careful monitoring.
research Efficacy of Topical Tofacitinib in Promoting Hair Growth in Non-Scarring Alopecia: Possible Mechanism via VEGF Induction
Topical tofacitinib may grow hair better than minoxidil by increasing VEGF and reducing inflammation.
research Emerging Therapies for Acne Vulgaris
New acne treatments show promise as alternatives to traditional therapies.
research Potential Medical Uses of Cannabigerol: A Brief Overview
CBG may help with various medical conditions but needs more human research to confirm safety and effectiveness.
research Evolving Approaches to Profiling the Microbiome in Skin Disease
New technologies help us better understand how skin microbes affect skin diseases.
research Alopecia Universalis After Alemtuzumab Treatment for Multiple Sclerosis: A Two-Year Follow-Up of Two Patients
Two patients developed complete hair loss after Alemtuzumab treatment for MS, with no regrowth after two years.