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Removing STAT5 from 3D-cultured human skin cells reduces their ability to grow hair.

Kaempferol helps skin stem cells grow and may improve skin thickness due to its 3-OH group.

Most patients experienced mild to moderate skin problems during a trial for a desmoid tumor treatment.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Air pollution worsens skin diseases and aging by causing inflammation and oxidative stress.

Alopecia areata is an autoimmune condition causing hair loss, influenced by genetics, stress, and diet, and may be prevented by a high soy oil diet.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Silver nanoparticles coated with substances like PEG showed strong antibacterial effects and improved wound healing when used in hydrogels.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Probiotic bacteria improved skin and hair health in aged mice.

Rhodococcus equi causes severe pneumonia in young foals, and effective vaccines are needed due to foals' weak immune responses.

Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.

Animal models have helped understand hair loss from alopecia areata and find new treatments.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

Costunolide may have multiple health benefits, including promoting hair growth and protecting against cancer and diabetes, but more research is needed.

Zinc deficiency in children can cause skin issues and can be serious if not diagnosed and treated properly.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Air pollution (PM10) increases skin inflammation and aging by reducing collagen and may trigger a repair response in skin cells.

Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.

Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.

Children with atopic dermatitis often have sleep problems due to itching and may benefit from melatonin, which helps with sleep and skin symptoms.

People with polycystic ovary syndrome have a higher chance of having chronic thyroiditis.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

The document concludes that while there are various treatments for Alopecia Areata, there is no cure, and individualized treatment plans are essential due to varying effectiveness.