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No single ideal JAK inhibitor for alopecia areata has been determined; JAK3 inhibitors may be promising with fewer side effects.

Topical JAK inhibitors can effectively treat alopecia areata and vitiligo by modulating immune responses.

Janus kinase inhibitors show promise in treating alopecia areata but need better topical formulations.

Thermal spring waters and their microbes could be good for skin health and treating some skin conditions in skincare products.

A vitamin D receptor mutation causes rickets and affects immune responses.

Booster shots of mRNA vaccines for COVID-19 increased protective antibodies without worsening autoimmune skin conditions in patients.

Scalp psoriasis features reversible hair loss and specific immune activation, with no significant hair follicle damage.

Ulcerative colitis can cause skin issues due to immune system problems.

Chemical exposure may contribute to the rise in atopic diseases and needs more research.

Early diagnosis and aggressive treatment are crucial for Cicatricial Alopecia, and treatment effectiveness varies among patients.

Targeting the skin's endocannabinoid system could help treat skin disorders.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Keratin 17 is modified by RSK1 in response to growth and stress, affecting skin growth and stress response.

The document concludes that certain mutations may contribute to the inflammation in hidradenitis suppurativa and suggests that targeting TNFα could be a treatment strategy.

Icariin helps mouse hair grow by boosting a growth factor in skin cells.

Immune checkpoint inhibitors can cause skin issues but are linked to better cancer outcomes.

ECM-inspired wound dressings can help heal chronic wounds by controlling macrophage activity.

A Chinese family had a child with a specific gene mutation causing vitamin D-resistant rickets, but the child improved with calcium and low-dose calcitriol.

Narrowband UVB treatment increases certain gene expressions in psoriasis skin and improves symptoms.

Alopecia areata treatment should be personalized, using topical or systemic therapies based on severity, with promising options like JAK inhibitors needing more research.

TNC+ fibroblasts play a key role in skin inflammation by interacting with T cells.

Up to half of people experience itchy scalp, often due to skin conditions like seborrheic dermatitis or psoriasis, and treatments vary based on the specific cause.

Botulinum toxin type A significantly reduces scalp psoriasis severity compared to placebo.

Japanese patients with alopecia areata often have a higher BMI and consume more vitamin C, fruit, and retinol, which may affect their condition's development or severity.

NK cells play a role in skin diseases like eczema and psoriasis.

sPLA2-IIE is crucial for normal hair follicle structure and skin health.

Phospholipase A2 enzymes play key roles in skin health and disease.

Using mesenchymal stem cells or their exosomes is safe for COVID-19 patients and helps improve lung healing and oxygen levels.

Paris polyphylla saponins may effectively treat acne due to their antibacterial and anti-inflammatory properties.

People with severe hair loss have lower zinc levels in their blood.