research Olfactory Receptor OR2AT4 Regulates Human Hair Growth
A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.
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research Experimental and Early Investigational Drugs for Androgenetic Alopecia
New hair loss treatments may include topical medications, injections, and improved transplant methods.
research Off-Label Uses of Retinoids in Dermatology
Retinoids are effective for various skin conditions and hair loss but have serious side effects, so low doses are recommended.
research Caffeine and Its Role in Regulating Androgenetic Alopecia
Caffeine can potentially treat common hair loss by counteracting hair follicle shrinkage caused by hormones.
research Adenosine Stimulates Fibroblast Growth Factor-7 Gene Expression Via Adenosine A2b Receptor Signaling in Dermal Papilla Cells
Adenosine may promote hair growth by increasing FGF-7 levels in dermal papilla cells.
research Human Scalp Hair Follicles Are Both a Target and a Source of Prolactin, Which Serves as an Autocrine and/or Paracrine Promoter of Apoptosis-Driven Hair Follicle Regression
Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.
research Cell Death in the Skin: Mechanisms and Implications
Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.
research Accelerated Endothelial to Mesenchymal Transition Increased Fibrosis via Deleting Notch Signaling in Wound Vasculature
Disrupting Notch signaling in blood vessels increases scarring during wound healing in mice.
research Involvement of ILC1-Like Innate Lymphocytes in Human Autoimmunity: Lessons from Alopecia Areata
ILC1-like cells can cause alopecia areata by attacking hair follicles.
research Immune Cell Regulation of the Hair Cycle
Immune cells affect hair growth and could lead to new hair loss treatments.
research Regenerative Medicine of Epidermal Structures
New treatments for skin and hair repair show promise, but further improvements are needed.
research Editor's Evaluation: Involvement of ILC1-Like Innate Lymphocytes in Human Autoimmunity, Lessons from Alopecia Areata
ILC1-like cells can independently cause alopecia areata by affecting hair follicles.
research Hormonal Regulation of Hair Follicles Exhibits a Biological Paradox
Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.
research A Genomic Approach to Susceptibility and Pathogenesis Leads to Identifying Potential Novel Therapeutic Targets in Androgenetic Alopecia
Genomic approach finds new possible treatments for hair loss.
research Immune Privilege Collapse And Alopecia Development: Is Stress A Factor
Stress may trigger hair loss by affecting immune protection in hair follicles.
research Adenosine Stimulates Growth of Dermal Papilla and Lengthens the Anagen Phase by Increasing the Cysteine Level via Fibroblast Growth Factors 2 and 7 in an Organ Culture of Mouse Vibrissae Hair Follicles
Adenosine helps hair grow longer and stronger by boosting certain growth factors and signaling pathways.
research Repurposing of Approved Cardiovascular Drugs
Some heart drugs show promise for other conditions, but more research is needed to confirm their effectiveness and safety.
research Vanillic Acid Stimulates Anagen Signaling via the PI3K/Akt/β-Catenin Pathway in Dermal Papilla Cells
Vanillic acid from wheat bran may promote hair growth by activating certain cell pathways and reversing hormone-related hair loss.
research Therapeutic Strategies for Treating Hair Loss
The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.
research Highly Upregulated Lhx2 in the Foxn1−/− Nude Mouse Phenotype Reflects a Dysregulated and Expanded Epidermal Stem Cell Niche
The Foxn1(-/-) nude mouse shows disrupted and expanded skin stem cell areas due to high Lhx2 levels.
research Genome-Wide DNA Methylation and Transcriptome Analyses Reveal the Key Gene for Wool Type Variation in Sheep
The SOSTDC1 gene is crucial for determining sheep wool type.
research The Roles of Non-Coding RNA in the Development and Regeneration of Hair Follicles: Current Status and Further Perspectives
Non-coding RNAs are important for hair growth and could lead to new hair loss treatments, but more research is needed.
research Hair Matters in Melanoma Biology
The document concludes that the immune-inhibitory environment of the hair follicle may prevent melanoma development.
research Functional Hair Follicle Regeneration: An Updated Review
Hair follicle regeneration possible, more research needed.
research Drug Discovery for Alopecia: Gone Today, Hair Tomorrow
Topical drugs and near-infrared light therapy show potential for treating alopecia.
research Can Plant-Derived Phytochemicals Provide Symptom Relief for Hair Loss? A Critical Review
Some plant-based chemicals may help with hair growth, but more research is needed to confirm their effectiveness.
research The Involvement of Androgens in Human Hair Growth
Androgens play a key role in hair growth and disorders like baldness and excessive hairiness.
research GWAS for Male-Pattern Baldness Identifies 71 Susceptibility Loci Explaining 38% of the Risk
Researchers found 71 genetic regions linked to male pattern baldness, which account for 38% of its genetic risk.
research Aberrant Activation of the Hedgehog Signaling Pathway in Malignant Hematological Neoplasms
Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.
research Network Pharmacology Reveals Curcuma Aeruginosa Roxb. Regulates MAPK and HIF-1 Pathways to Treat Androgenetic Alopecia
Curcuma aeruginosa Roxb. may help treat hair loss by affecting specific biological pathways.