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New genes linked to ichthyosis were found, but there's still no cure; treatment options are improving.

Thermoresponsive nanogels show promise for delivering medicine through the skin but need more safety testing and regulatory approval before clinical use.

Flightless I protein affects hair growth, with low levels delaying it and high levels increasing hair length in rodents.

The cornified envelope is crucial for skin's barrier function and involves key proteins and genetic factors.

The enzyme DHHC13 is essential for healthy hair and skin, and its deficiency leads to hair loss and skin problems.

Mutations in NIPAL4 cause skin issues by disrupting lipid layers, but some improvement is seen with topical treatment.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Vitamin D receptor is crucial for starting hair growth after birth.

A 3-month stay in space causes skin thinning, disrupts hair growth, and changes muscle-related genes in mice.

Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.

Drug repositioning offers hope for new, affordable treatments for a genetic skin disorder called ARCI.

Teak is a durable, termite-resistant wood with medicinal benefits.

New treatments for ichthyosis, like protein replacement and gene therapy, show promise and may become standard care.

Catalytic antibodies are early indicators and active participants in the development of systemic lupus erythematosus.

Patients with RASopathies are at risk for autoimmune disorders and should be routinely screened.

Androgen replacement therapy can improve libido and mood in women with severe androgen deficiency, but more research is needed on its long-term safety.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

ZDHHC13 is important for normal liver function and metabolism, affecting mitochondrial activity.

Mutant mice help researchers understand hair growth and related genetic factors.

NSG mice had the most mites, and genetic factors affect immune response and susceptibility.

The boy's severe skin disorder is caused by two new mutations in his TGM1 gene.

Hair loss in women linked to higher sexual dysfunction risk.

HPV genes in mice improve ear tissue healing by speeding up skin growth and repair.

DHT affects testicular development and regulates spermatogenesis in some fish.

The transgene likely activated an oncogene or interrupted a tumor suppressor gene, causing melanoma in mice.

Mice with a changed Hr gene lose and regrow hair due to changes in the gene's activity.

South Asian women with PCOS are more likely to have metabolic issues and central obesity, and simple measures like waist size and blood pressure can help identify these risks early.

Different types of PCOS have different levels of metabolic problems, with the most severe type showing the highest disturbances.

The document concludes that computational methods using networks and various data can improve the process of finding new uses for existing drugs.

Excipients greatly affect how well curcumin nanocrystals penetrate the skin and target hair follicles.