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Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Finasteride and minoxidil are effective for hair loss, but continued research is needed for better treatments.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Caffeine in cosmetics may reduce cellulite, protect skin, and stimulate hair growth, but more research is needed on its use and effects.

The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

Finasteride may cause slight depression and anxiety.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

Mice without the vitamin D receptor gene lose hair due to disrupted hair follicle cycles.

White lupin uses specific genes to grow root hairs and access phosphorus when it's scarce.

ZDHHC13 is important for normal liver function and metabolism, affecting mitochondrial activity.

Finasteride helps reduce heart issues and improves heart function.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

Captopril reduces heart mass, while minoxidil has opposite effects and side effects.

Children generally have milder SARS symptoms than adults, with good outcomes and no deaths reported, but long-term effects are unclear.

Mice with human gene experienced hair loss when treated with DHT.

Some alternative treatments for hair loss might work, but more research is needed.

Sex hormone treatments can increase muscle mass in older adults but have inconsistent effects on muscle function and may carry cardiovascular risks.

5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.

Minoxidil effectively treats hair loss, with better results in women.

Finasteride reduces new brain cells in male mice, possibly causing depression.

High androgen levels and genetic factors likely cause Becker's nevus and related symptoms.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.