80 citations,
May 2011 in “Nature Cell Biology” New methods have greatly improved our understanding of stem cell behavior and roles in the body.
31 citations,
November 2015 in “PloS one” Reducing Tyrosinase prevents mature color pigment cells from forming in mouse hair.
January 1978 in “Clin-Alert” A document listed serious side effects from various drugs, including deaths and diseases, emphasizing the importance of being aware of drug side effects.
12 citations,
October 1976 in “The BMJ” Syphilis can cause hair loss and treating the infection can reverse it.
3 citations,
May 2011 in “Journal of the American Academy of Dermatology” A woman's excessive hair growth around a leg ulcer was linked to a treatment with Prostaglandin E1 ointment.
86 citations,
December 2001 in “Experimental dermatology” Mutant mice help researchers understand hair growth and related genetic factors.
56 citations,
February 2010 in “PLOS ONE” Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.
16 citations,
January 2017 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” Managing frontal fibrosing alopecia and lichen planus pigmentosus is challenging due to resistant hair loss and skin discoloration.
11 citations,
May 2011 in “Journal of Cutaneous Medicine and Surgery” Break dancing on the head may cause a type of scarring hair loss that needs early treatment to prevent permanent damage.
5 citations,
January 2014 in “International Journal of Trichology” Hair loss on the lower legs is common in middle-aged men, usually harmless, and doesn't need treatment.
4 citations,
July 2014 in “International Journal of Dermatology” Twins had rare skin cysts likely due to genetics.
1 citations,
January 2013 in “International Journal of Trichology” The conference discussed various hair disorders and treatments, including the use of topical steroids, high doses of cetrizine, and hair grafting, as well as the psychological impact of hair loss.
1 citations,
January 2001 in “American Journal of Kidney Diseases” Hair loss in three Southeast Asian women with kidney failure may be linked to their anemia treatment with erythropoietin.
March 1988 in “Reactions (Auckland)” Birth control pills can improve or cause acne and hair issues, with improvements more common, and may affect skin pigmentation.
1039 citations,
February 2009 in “Nature Reviews Molecular Cell Biology” Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.
551 citations,
November 2013 in “Nature” Certain mature cells in mouse lungs can turn back into stem cells to aid in tissue repair.
508 citations,
February 2007 in “Cell” Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.
254 citations,
January 2012 in “Nature Reviews Molecular Cell Biology” Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.
245 citations,
January 2018 in “Bone Research” TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.
211 citations,
April 2013 in “Development” More dermal papilla cells in hair follicles lead to larger, healthier hair, while fewer cells cause hair thinning and loss.
173 citations,
January 2014 in “Nature Cell Biology” Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.
166 citations,
April 2012 in “Journal of The American Academy of Dermatology” Mostly postmenopausal Caucasian women get Frontal Fibrosing Alopecia, which often includes eyebrow loss and has limited treatment success.
160 citations,
March 2009 in “Seminars in Cutaneous Medicine and Surgery” New insights show Lichen Planopilaris is a rare, scarring hair loss condition, hard to treat, mainly affecting middle-aged women, and significantly impacts mental health.
144 citations,
September 2006 in “Clinics in Dermatology” Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.
140 citations,
March 2013 in “The journal of immunology/The Journal of immunology” Memory regulatory T cells need IL-7, not IL-2, to stay in peripheral tissues.
137 citations,
June 2005 in “Climacteric” Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.
134 citations,
January 2011 in “Development” Adam10 enzyme is crucial for healthy skin and proper Notch signaling.
131 citations,
May 2015 in “Experimental Dermatology” Microneedles help improve skin appearance and deliver skin treatments effectively, but safety concerns need more research and regulation.
125 citations,
December 2016 in “Molecules” Substances from Chinese medicines show promise for immune support and disease prevention, but the way they are processed affects their effectiveness.
117 citations,
March 2013 in “Journal of the European Academy of Dermatology and Venereology” No effective treatment for frontal fibrosing alopecia was found, but oral 5-alpha-reductase inhibitors had the best response; for lichen planopilaris, topical corticosteroids were commonly used but had a high relapse rate.