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This research describes methods to activate melanocyte stem cells during hair follicle regeneration and to isolate melanocytes from neonatal mouse skin, with the aim of studying melanogenesis for potential clinical applications.

This study reports a new method for selectively synthesizing finasteride Form-I in good yield using water as an ecofriendly solvent at room temperature.

This study found that dexamethasone treatment inhibited the inflammatory response and the induction of ornithine decarboxylase activity in mouse skin after TPA application, although the effect on ODC was weaker during the hyperplastic stage.

This review discusses the pathophysiology of alopecia areata, highlighting the role of CD8 cytotoxic T cells and the upregulation of JAK signaling pathways; it reports no new experimental results.

This collection presents a photogallery on the follicular occlusion syndrome, uniting diseases like hidradenitis suppurativa under shared pathogenesis, but reports no new clinical results.

In this study, progesterone showed anticonvulsant effects in mice via a mechanism that is at least partially independent of its metabolism to THP, without significant psychotoxicity.

This dissertation reports that Lrig1 and Lgr6 mark distinct stem cell populations in mouse hair follicles, playing roles in tissue regeneration and tumor development, with Lgr6 regulating Wnt signaling and restraining epidermal lineage commitment.

In this study, the authors found that targeting mTORC1 with rapamycin inhibited TPA-induced skin tumor promotion by affecting keratinocyte proliferation, including critical stem cell populations in the mouse epidermis.

This study concluded that their modified immunohistochemical staining protocol can determine the ABO blood group of both medullated and non-medullated scalp hair, potentially aiding in hair sample screening before DNA analysis.

This study found that mrp/plf-mRNA expression in murine skin increases in response to different tumor promoters, suggesting its potential as a short-term biomarker for chemical carcinogenesis.

Scientists found key proteins and genes that affect skin and hair health, and identified potential new treatments for hair loss, skin disorders, and wound healing.

This study found that exposure to 12-O-tetradecanoyl-phorbol-13-acetate in mouse skin caused changes in claudin expression and localization, indicating disruption and eventual recovery of the epidermal barrier.

This study concluded that allele-specific PCR (AS-PCR) is more reliable than tetra-primer ARMS-PCR for genotyping the SNP rs1998076 due to better stability and interpretability.

Cyclosporin doesn't stop hair loss.

Oral cyclosporin doesn't stop hair loss.

This review discusses the features of regulatory T cells and the modulation of Foxp3, emphasizing post-translational modifications' impact on Treg function but reports no new clinical results.

This study found that 1-butyl-3-methylimidazolium tetrafluoroborate is the optimal ionic liquid solvent for extracting quercetin from Nothopanax scutellarium leaves.

In this study, cepharanthine and tetrandrine demonstrated efficacy against SARS-CoV-2 in a cell-based infection assay, with cepharanthine showing a lower IC50 value.

In this study, researchers analyzed over 5,000 T cells per sample using scRNA+TCR-seq technology and found that dual TCR Tregs are present in high proportions across various mouse tissues, showing unique TCR pairing patterns, V(D)J usage, and mRNA expression compared to single TCR Tregs.

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Epirubicin is as effective as doxorubicin for cancer treatment with less heart damage, but doesn't work on doxorubicin-resistant cancers.

This study describes a new method for extracting red mordant dyes from wool fibers using ethylene diamine tetraacetic acid and N,N-dimethyl formamide, preserving the fibers for further examination.

This paper reviews current cell therapies in medicine, highlighting hematopoietic stem cell transplants as a foundational success and the growing application of genetically modified cells like CAR-T and mesenchymal stem cells for various diseases, including blood disorders and autoimmune conditions.

This study found that estradiol and other sex steroids reduced the capture of monocytes by human endothelial cells in vitro, potentially inhibiting the formation of atherosclerosis by promoting nCAM polysialylation, which interferes with leukocyte tethering to the vascular endothelium.

This article discusses the structure and protective function of pangolin scales, emphasizing their composition of α-keratins and β-keratins, and highlights evolutionary keratin diversification in tetrapods; it reports no new empirical findings.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

In this study, researchers successfully established a stable transgenic sheep fibroblast cell line containing an artificially synthesized spider dragline silk protein gene.

This study describes a mouse model for Marie Unna Hereditary Hypotrichosis, identifying mutations in the hairless gene that result in sparse or absent hair and cyst-like hair follicles.

This study found that a sucrose-based crosslinker can effectively straighten hair and maintain durability in high humidity and through repeated washings without affecting the hair's tensile properties or causing surface damage.

This study found that procyanidin B-2 may promote hair growth by reducing expression and inhibiting translocation of PKC isozymes in murine hair epithelial cells.