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The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

This review discusses the role of androgens in the progression of cardiovascular disease and explores novel therapeutic targets without reporting new clinical results.

This review discusses the role of 5α-reductase in prostate development and BPH, and reports no new clinical results; ongoing trials are exploring dual isozyme inhibitors for improved treatment efficacy.

This review discusses the complex effects of testosterone on the brain, emphasizing sex differences, and reports no clinical results; the authors highlight the inconsistencies in current study findings.

This review discusses the effects of hormonal treatments on the physical and mental health of transgender individuals, reporting significant reductions in mental health issues following treatment, but calls for more research on long-term and nonbinary outcomes.

This study reported that treatment with gonadotropin-releasing hormone analogs and cross-sex hormones appears appropriate for carefully selected youth with gender dysphoria, but long-term safety needs further investigation.

New treatments for male hypogonadism are effective and should be personalized.

This review offers transgender hormone treatment guidelines to assist healthcare providers in improving transgender patients' access to and outcomes of medical care, but it reports no new clinical results.

This article reviews the use of cross-sex hormonal therapy in transmen and reports that it is reasonably safe, suggesting monitoring should be frequent initially but can be less frequent over time.

In this study, stress experienced by transmen during early stages of gender transition was associated with reduced nocturnal blood pressure decline and increased C-reactive protein levels.

This study developed a sensitive and specific method for detecting testosterone in horse hair, finding trace amounts in samples for up to five months after administering a single dose.

This review discusses the potential of DHEAS and testosterone treatments to increase muscle mass in older men with sarcopenia, while effects on muscle function and physical performance remain unclear, and calls for further research on optimized approaches.

This article provides a framework for understanding hair disorders and treatment options in transgender individuals undergoing hormonal therapy and reports no new clinical results.

This article discusses the development of a transdermal testosterone patch for postmenopausal women to deliver physiological testosterone levels but reports no new clinical results, highlighting a need for long-term safety data.

This study suggests that gender-affirming testosterone therapy in transgender men is generally safe and effective with adequate screening and monitoring, although high-quality long-term studies are lacking.

Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.

This review discusses the physiological basis, history, and current development of male hormonal contraception, highlighting its potential risks and benefits, but reports no new research findings.

This review examines the benefits and potential risks of androgen replacement therapy for male hypogonadism but reports no new clinical results; the authors highlight the need for careful risk assessment, especially in older men.

This review discusses cross-sex hormone therapy for managing gender dysphoria in transsexual individuals and reports no new clinical results; it highlights the need for education and culturally sensitive training for healthcare professionals.

The document concludes that there are still unknowns about the effectiveness, risks, and detection of performance-enhancing drugs, and doping remains a challenge.

In this review, the authors examined guidelines and literature on the non-operative treatment of gender dysphoria, highlighting the importance of personalized, multidisciplinary care, and noting that such treatment is generally safe and effective according to WPATH and Endocrine Society recommendations.

This study found that experienced Australian prescribers of hormone therapy for transgender adults often follow international guidelines but highlight the need for better training and specific local guidelines.

This study found that an alcoholic extract of Glycyrrhiza glabra significantly reduced prostate weight and serum testosterone in castrated rats given testosterone, indicating potential antiandrogenic properties.

This article discusses the basic care and issues primary care providers should consider when treating transgender patients, but it reports no new clinical results.

This review summarizes existing clinical guidelines for hormonal therapy in gender dysphoria, observing similarities in international practices and emphasizing the need for more evidence-based research, particularly on GnRH agonists for both trans women and men.

This study observed that integrating best practices for anabolic androgenic steroid users into Swiss primary care is feasible and well-accepted, though current doping laws hinder adequate medical care for this population.

This source suggests that migraine prevalence increases in transgender women using oestrogen and decreases in transgender men using testosterone, with high oral oestrogen doses in transgender women potentially linked to aura risk.

This review discusses the role of androgens in women's sexual health and highlights the need for further research on androgen replacement therapy to optimize quality of life, but reports no new clinical results.

This review suggests that dihydrotestosterone pretreatment may improve cosmetic outcomes in hypospadias repair, but more randomized trials are needed to determine its effectiveness due to currently limited evidence.

This article reviews the role of testosterone in sexual health, supporting Testosterone Replacement Therapy as an effective treatment for Hypoactive Sexual Desire Disorder in postmenopausal women, though more research is needed on its long-term effects and applicability to premenopausal women.