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The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Muscles can make their own androgens, which may help muscle growth.

Using anabolic-androgenic steroids can harm men's reproductive health and increase the risk of heart problems and death.

Healthcare providers need better education and resources to give competent and sensitive care to transgender patients.

The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Androgen use may increase the risk of stroke, but more research is needed.

Some common medications may harm male fertility by affecting hormones, sperm production, and sexual function.

Hormone therapy in transgender individuals can increase acne and affect hair growth and loss.

Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.

Gender-affirming hormone therapy changes hair growth in transgender people, with feminizing therapy reducing hair and masculinizing therapy increasing it, but sometimes additional treatment is needed.

Hormone treatment for transsexual individuals is effective but carries risks like thromboembolic events and mood changes, with most side effects being minor and reversible.

Managing side effects of endocrine therapy is crucial to improve adherence and survival in breast cancer patients.

Hormonal male contraception is effective and could be market-ready, but more research is needed to ensure safety for all ethnic groups.

AGA treatments like minoxidil and LLLLT are safe and effective for gender minority patients.

Finasteride effectively treats hair loss in transgender men with few side effects.

Finasteride doesn't affect erections much, but may decrease libido in men.

Minoxidil helped a boy regrow his hair after intense chemotherapy for leukaemia.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

Chinese medicine may help hair growth and reduce hair loss in androgenetic alopecia.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Too much male hormone is the main cause of Polycystic Ovary Syndrome.

Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

Non-binary transgender individuals need personalized hormonal treatments for better well-being and quality of life.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.

The article concludes that dermatologists should prescribe lifestyle drugs carefully and consider mental health treatments for patients with disorders like BDD.

The document concludes that gender-affirming treatments are essential for transgender individuals and outlines safe hormone therapy practices.

Hormone therapy increases facial and body hair in transgender men, while hair removal improves well-being in transgender women, but cost is a barrier as insurance often doesn't cover it. Dermatologists can use various treatments for these hair issues.