research Androgenetic Alopecia and Microinflammation
Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.
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research Finasteride
Finasteride effectively treats baldness but may cause sexual side effects.
research Effects of In Utero Exposure to Finasteride on Androgen-Dependent Reproductive Development in Male Rats
Exposure to finasteride in the womb caused lasting reproductive issues in male rats.
research Clinical Management of Youth with Gender Dysphoria in Vancouver
Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.
research Steroid 5α-Reductases and 3α-Hydroxysteroid Dehydrogenases: Key Enzymes in Androgen Metabolism
Key enzymes control androgen levels, affecting hormone activity and potential treatments.
research Polycystic Ovary Syndrome, Androgen Excess, and the Risk of Nonalcoholic Fatty Liver Disease in Women: A Longitudinal Study Based on a United Kingdom Primary Care Database
Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.
research Disorders Linked to Insufficient Androgen Action in Male Children
Insufficient androgen action in male fetuses can cause genital development issues due to genetic mutations or environmental chemicals.
research Management of Transgenderism
Transgender treatment includes hormones and surgery, but long-term effects are unknown and counseling is needed.
research Treatment of Obstructive Sleep Apnea Improves Cardiometabolic Function in Young Obese Women with Polycystic Ovary Syndrome
Treating sleep apnea in young obese women with PCOS can improve heart health and insulin sensitivity.
research Androgen Dependence of Hirsutism, Acne, and Alopecia in Women
Hirsutism is more linked to high androgen levels than acne or hair loss, and a mix of hormonal tests is best for diagnosis; certain treatments can reduce symptoms.
research Role of 5α-Reductase in Health and Disease
5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.
research Topical Minoxidil Solution (1% and 5%) in the Treatment of Alopecia Areata
Minoxidil solution helps hair regrowth in alopecia areata, with 5% being more effective.
research Female Pseudohermaphroditism Caused by a Novel Homozygous Missense Mutation of the GR Gene
A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.
research 5α-Reductase Isozymes and Androgen Actions in the Prostate
5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.
research Clinical Pharmacokinetics and Pharmacodynamics of Finasteride
Finasteride helps regrow hair and shrink prostate by reducing DHT, with some sexual side effects.
research Metformin Improves Polycystic Ovary Syndrome Symptoms Irrespective of Pre-Treatment Insulin Resistance
Metformin helps with PCOS symptoms no matter the patient's initial insulin resistance or weight.
research Global Adiposity and Thickness of Intraperitoneal and Mesenteric Adipose Tissue Depots Are Increased in Women With Polycystic Ovary Syndrome
Women with PCOS have more body fat and thicker fat layers in certain abdominal areas than women without PCOS.
research Reproductive Seasonality and Maturation Throughout the Complete Life-Cycle in the Mouflon Ram (Ovis Musimon)
Mouflon rams mature gradually with changes in body, horns, and hormones linked to age and seasons, reaching full sexual maturity well after puberty.
research Adverse Effects Associated with Long-Term Administration of Azole Antifungal Agents
Long-term use of azole antifungals can cause hair loss, hormonal imbalances, and severe skin reactions.
research Management of Sexual Dysfunction in Postmenopausal Breast Cancer Patients Taking Adjuvant Aromatase Inhibitor Therapy
Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.
research Prevalence of Polycystic Ovaries in Women with Androgenic Alopecia
Women with androgenic alopecia are more likely to have polycystic ovaries and higher androgen levels, which may indicate PCOS.
research Three-Month Treatment With a Long-Acting Gonadotropin-Releasing Hormone Agonist of Patients With Benign Prostatic Hyperplasia: Effects on Tissue Androgen Concentration, 5α-Reductase Activity and Androgen Receptor Content
A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.
research Heavily Hunted Wolves Have Higher Stress and Reproductive Steroids Than Wolves With Lower Hunting Pressure
Heavily hunted wolves have higher stress and reproductive hormone levels.
research Diagnosis of Hyperandrogenism: Biochemical Criteria
The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.
research Prevalence of Polycystic Ovaries in Women with Self-Reported Symptoms of Oligomenorrhoea and/or Hirsutism: Northern Finland Birth Cohort 1966 Study
Women with irregular periods and/or excessive body hair are more likely to have polycystic ovaries, and this condition is linked to higher health risks.
research Androgenetic Alopecia in Men and Women
Androgenetic alopecia involves genetics, hormones, and can be treated with medications or surgery.
research Treatment of Hirsutism with a Gonadotropin-Releasing Hormone Agonist (Nafarelin)
Nafarelin may effectively treat excessive hair growth in women by reducing certain hormone levels.
research Comparison of Finasteride Versus Spironolactone in the Treatment of Idiopathic Hirsutism
Finasteride reduces hair growth better, but spironolactone has more side effects.
research Androgenic Activity in Autism
Some autistic children may have higher levels of male hormones, which could be linked to aggression.
research Comparison of Finasteride Versus Flutamide in the Treatment of Hirsutism
Finasteride is a safe, effective treatment for hirsutism with fewer side effects.