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Some antiandrogens may lower testosterone better than others, but it's unclear which is best for feminization in transgender women; more research is needed.

Human beard hair follicles change testosterone into other related hormones, but don't much change androstenedione into testosterone.

Testosterone is made by Leydig cells, is active when not bound to proteins, and works by binding to receptors in muscles and other tissues.

Testosterone and its byproducts help support male sexual behavior through different pathways in the brain and body.

Testosterone affects hair follicles differently across body sites, with beard hair follicles showing more activity of a specific enzyme and presence of androgen receptors compared to scalp hair.

Testosterone treatment in transgender teens can worsen acne, requiring careful treatment due to mental health and medication side effects.

Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.

The substance MK386 effectively blocked testosterone conversion and reduced cell growth in certain skin cells, but inhibiting 5α-reductase alone may not greatly improve acne.

Androgens, male hormones, play a role in both men and women's health, and testosterone therapy can help women with low levels, but it's not suitable for pregnant or lactating women, or those with certain conditions.

These drugs cause hair growth without affecting testosterone or adrenal hormones.

New and future treatments for male hypogonadism include various forms of testosterone therapy and emerging drugs.

Hormone therapy with estradiol and spironolactone can regrow scalp hair in transgender women by lowering testosterone to female levels.

Researchers found potential urine markers for polycystic ovary syndrome, including testosterone-glucuronide and 11α-hydroxyprogesterone, which may help diagnose the condition.

Oophorectomy lowers testosterone and estrogen levels in both premenopausal and postmenopausal women, with postmenopausal women still producing significant testosterone.

Most hirsutism cases are due to PCOS, and treatment focuses on lowering testosterone and blocking its effects.

Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.

Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.

Chromium supplements don't improve insulin, hormone levels, or cholesterol in women with PCOS but raise testosterone levels.

Nearly half of the studied men with long COVID had low testosterone, including younger men.

A woman developed male traits from accidental contact with her husband's testosterone gel.

Sex hormones like estrogen and testosterone may affect COVID-19 severity differently in men and women, potentially influencing prevention and treatment strategies.

The document concludes that careful evaluation is needed to diagnose PCOS correctly due to similar symptoms in other conditions, and accurate testosterone level measurement is crucial.

Curcumin and its derivatives can block an enzyme important for making testosterone, with one derivative being particularly strong.

Male rats have more somatostatin neurons than females due to testosterone converting to estrogen during early development.

Low testosterone in men is a risk factor for a specific heart rhythm issue, and testosterone treatment may help prevent it.

Sex hormones may affect COVID-19 severity, with estrogen possibly reducing risk and testosterone potentially increasing it.

Indian women with PCOS from Delhi and Srinagar show different symptoms, with Delhi women having higher obesity and blood sugar issues, and Srinagar women showing more hair growth and testosterone levels.

DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.

Dihydrotestosterone specifically binds to hamster sebaceous glands, with a higher affinity than testosterone.

Liquorice may reduce testosterone and affect male reproductive organs, potentially helping treat conditions like prostate cancer.