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5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Steroids, particularly estrogens and 5α-reductase inhibitors, affect blood vessel-related hair growth processes in hair follicle cells.

The effects of estrogen on human scalp hair growth are unclear and need more research.

Men born very underweight had higher estrogen levels but normal reproduction compared to normal birth weight men.

Older men with low levels of a testosterone byproduct had a higher chance of developing an irregular heartbeat.

Levothyroxine is less effective in men with early-onset male-pattern baldness.

Genes and epigenetic changes are important in the development of Polycystic Ovary Syndrome.

Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.

The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.

Finasteride shows promise for female hair loss, but more research needed.

The document concludes that hair loss is complex, affects many people, has limited treatments, and requires more research on its causes and psychological impact.

Insulin resistance contributes to hormone imbalances in many women with polycystic ovary syndrome.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

The document concludes that treating PCOS requires a combination of drugs to manage reproductive and metabolic symptoms, with more research needed on combination therapies.

A woman was the first known case to have both polycystic ovary syndrome and autoimmune polyglandular syndrome type 2, suggesting a need to check for both conditions in similar patients.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

PCOS starts in adolescence with hormonal issues, leading to adult health problems, and early treatment is crucial.

DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.

COVID-19 might worsen symptoms and progression of benign prostatic hyperplasia, possibly due to inflammation and metabolic disturbances in the prostate gland. More research is needed to confirm this.

Herbs can potentially treat hair loss by inhibiting a key enzyme and promoting hair growth, and deficiencies in zinc, biotin, and iron are linked to hair loss.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.

Topical estrogen helps hair growth in menopausal women with no major side effects.

Finasteride reduces inflammation and improves immune response after trauma by altering hormone levels.

Vitamin D and estrogen may help protect heart and kidney health, and maintaining sufficient vitamin D levels could be especially beneficial for African Americans, postmenopausal women, and people with chronic kidney disease.

The document concludes that individualized treatment and lifestyle changes are important for managing menopause symptoms and health risks.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.