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Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Leptin helps start the growth phase of hair.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

Skin diseases linked to insulin resistance should be managed to prevent diabetes and reduce heart disease risk.

Sex hormones, especially estradiol, can change chicken feather shapes and colors.

ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.

Finasteride negatively affects fish reproduction and gonadal development.

A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.

Androgens can both increase and decrease hair growth in different parts of the body.

Myrtle has various health benefits and potential for medicine development.

Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

CYP2B12 enzyme in skin cells converts arachidonic acid into specific bioactive lipids.

Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.

Different women's hair and skin glands respond to hormones in varied ways, which can cause unwanted hair growth even with normal hormone levels, and more research is needed to treat this effectively.

Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.

Sex hormone treatments can increase muscle mass in older adults but have inconsistent effects on muscle function and may carry cardiovascular risks.

5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.

Testosterone may influence COVID-19 severity and outcomes.

Higher testosterone levels can increase the risk of certain diseases like type 2 diabetes in women and prostate cancer in men, but can also protect against autoimmune diseases and hair loss. It also affects body fat and bone density.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

Finasteride worsens seizures in epilepsy rats and speeds up epileptogenesis in mice.

Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.

High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.

Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.

Low doses of BPA can increase prostate growth and change hormone levels in adult rats.

Higher BMI and lower testosterone are linked to more aggressive prostate cancer.

Dihydrotestosterone increases growth and spread of human brain cancer cells, and blocking its formation might help treat this cancer.