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Transfollicular drug delivery is promising but needs more research to improve and understand it better.

Licorice root extract may promote hair growth in female rats.

150 kHz electromagnetic radiation might help improve PCOS in rats.

5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.

Finasteride has different absorption and metabolism in male and female rats, with higher concentrations in certain organs and mostly excreted through feces.

Trazodone and chlorpromazine may help treat sexual dysfunction caused by finasteride and SSRIs.

Different types of stem cells in the skin contribute to the variety of melanoma forms.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Skin symptoms can indicate endocrine disorders and have various treatments.

Letrozole reduces seizures but not brain damage in mice.

Hormone levels in hair vary across the head, with the highest concentration of a key hormone linked to hair loss at the top.

Dihydrotestosterone makes arteries stiffer in female mice by reducing estrogen receptor expression.

Having PCOS does not make hidradenitis suppurativa worse.

Natural extracts like peppermint and rosemary oils are effective for hair growth and scalp health.

The new rodent model successfully mimics non-lean human PCOS symptoms.

Finasteride changes hormone levels and certain proteins in rats, but these effects can be reversed after stopping the drug.

A 36-year-old person with a female appearance but male chromosomes was diagnosed with a rare enzyme deficiency affecting sexual development.

Topical finasteride might be a good alternative for hair loss treatment with fewer side effects, but more research is needed.

Men may experience long-term sexual dysfunction after stopping Finasteride.

Certain gene variations are significantly linked to hair loss, especially in white people.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.

Women with irregular periods and/or excessive body hair are more likely to have polycystic ovaries, and this condition is linked to higher health risks.

The review recommends hormone replacement therapy for women with premature ovarian insufficiency to manage symptoms and protect health, with specific approaches for different groups.

Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.

Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.

Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.

Using β-cyclodextrin derivatives improves the solubility and bioavailability of steroidal drugs.