13 citations,
January 2019 in “Endocrine journal” Dihydrotestosterone treatment can help penis growth in boys with 5α-reductase deficiency but doesn't fully normalize size after puberty.
March 2004 in “Current Sexual Health Reports” Testosterone's role in women's sex drive is unclear and needs more research, as low levels don't always mean less sexual interest and high levels can cause side effects.
162 citations,
April 2016 in “The Lancet Diabetes & Endocrinology” Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.
124 citations,
March 2012 in “JAMA” Testosterone's muscle-building effects do not require its conversion to DHT.
249 citations,
November 2003 in “Clinical endocrinology” Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.
26 citations,
January 2020 in “Przegląd Menopauzalny” Menopausal women have higher androgen levels, which can cause symptoms like facial hair growth and low sexual desire.
1 citations,
December 2019 in “Frontiers in endocrinology” Higher androgen levels during puberty are linked to shorter adult height in boys with Silver-Russell syndrome.
11 citations,
May 1996 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.
May 2015 in “Endocrinología y nutrición” The conclusion is that adult males with muscle weakness and hormonal imbalances should be tested for Kennedy's disease.
2 citations,
April 2023 in “Pharmaceuticals” Testosterone therapy for postmenopausal women appears safe and may protect against heart disease, but requires constant monitoring and more research for long-term effects.
February 2023 in “Vaccines” COVID-19 may harm male reproductive health and lower testosterone levels, potentially affecting fertility and causing erectile dysfunction. More research is needed.
3 citations,
January 2011 in “Female pelvic medicine & reconstructive surgery” Hormones significantly affect women's sexual function, and more research is needed to improve treatments for sexual dysfunction with minimal side effects.
18 citations,
August 1985 in “European journal of endocrinology” Cyproterone acetate is effective for treating hirsutism, but some patients may feel worse on low-dose maintenance therapy.
Hormonal treatments can help with hair loss, acne, and excess hair growth, but it takes 3-6 months to see results and patients should know the possible side effects.
20 citations,
June 2010 in “International Journal of Dermatology” Women with mild acne are more likely to have polycystic ovary syndrome (PCOS) than those without acne.
1 citations,
January 2015 in “Hair therapy & transplantation” Some supplements and hormones can increase hair loss by raising DHT levels.
66 citations,
March 1998 in “Mayo Clinic Proceedings” Removing a testosterone-producing tumor cured a woman's sleep apnea and other symptoms.
3 citations,
October 1995 in “International Journal of Dermatology” Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.
93 citations,
January 1996 in “Clinical Pharmacokinectics” Finasteride helps regrow hair and shrink prostate by reducing DHT, with some sexual side effects.
2 citations,
January 2023 in “Research Square (Research Square)” Managing emotional distress, obesity, insulin resistance, and high male hormones is crucial for improving well-being in women with PCOS.
5 citations,
June 2010 in “Endocrinología y Nutrición” Diagnosing and managing PCOS in teens is hard, but early diagnosis and lifestyle changes are key, and more research is needed for long-term health.
49 citations,
February 2009 in “Maturitas” Short-term testosterone therapy in women seems safe with few mild side effects, but long-term effects need more research.
3 citations,
September 2014 in “Journal of obstetrics and gynaecology Canada” Menopause often leads to lower sexual desire and discomfort during sex, but treatment should be personalized and only if it bothers the woman.
77 citations,
June 2015 in “Nature Reviews Urology” Some common medications can harm male fertility, but many effects can be reversed.
46 citations,
January 2008 in “Climacteric” Testosterone therapy can help improve sexual desire and function in postmenopausal women but may cause side effects and is not FDA-approved for this use.
8 citations,
January 2003 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Women with myotonic dystrophy might get diseases related to male hormones because their body tissues are extra sensitive to these hormones.
14 citations,
September 2007 in “Steroids” The study concluded that androstendione and DHEA are important for diagnosing high male hormone levels in women with excessive hair growth.
10 citations,
February 2007 in “Current Opinion in Endocrinology, Diabetes and Obesity” Low birthweight and rapid weight gain after birth may increase the risk of developing polycystic ovary syndrome.
25 citations,
August 2006 in “Human Reproduction” Oral contraceptives lower testosterone levels in women, especially those with certain genetic traits, and may be linked to increased breast cancer risk.
77 citations,
June 2006 in “Best Practice & Research Clinical Endocrinology & Metabolism” The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.