8 citations
,
May 1996 in “Endocrinology” This study found that the androgen precursors DHEA and androstenedione stimulated androgen-sensitive parameters in the sebaceous glands of the skin in castrated male hamsters.
8 citations
,
January 1986 in “Journal of hepatology” This study suggests that hepatocellular carcinoma in cirrhotic men is associated with altered sex-steroid metabolism, indicated by lower testosterone and 5 alpha-dihydrotestosterone levels compared to cirrhosis alone.
7 citations
,
April 2023 in “Biomedicines” This study found that sex hormones, specifically non-aromatizable androgens like DHT and A/T, significantly increase inflammatory cytokine expression in human adipocytes when stimulated by LPS.
7 citations
,
January 2019 in “Headache” This source suggests that migraine prevalence increases in transgender women using oestrogen and decreases in transgender men using testosterone, with high oral oestrogen doses in transgender women potentially linked to aura risk.
6 citations
,
January 2019 in “F1000Research” This study found that triglycerides, testosterone, and SHBG levels were associated with hyperandrogenism in women with PCOS, while FGS was not linked to this condition.
6 citations
,
October 2018 in “Endocrinology” This study indicates that sheep prenatally androgenized with testosterone show wool fiber diameter changes that parallel the increased hair diameter in women with polycystic ovary syndrome.
6 citations
,
June 2017 in “Reproductive Biomedicine Online” This study found that women with polycystic ovary syndrome in China had elevated androgen levels compared to healthy controls, and suggests body weight management and SHBG and FAI testing are recommended for these women.
6 citations
,
April 2009 in “Fertility and Sterility” Finasteride helps induce ovulation in nonresponder PCOS women.
6 citations
,
September 1998 in “The Journal of The British Menopause Society” This review discusses the changes in androgen levels with age in women and the potential benefits of testosterone replacement therapy as part of hormone replacement therapy for postmenopausal women, but it reports no new clinical results.
5 citations
,
December 2021 in “Physiological Research” This paper reviews the role of androgens in SARS-CoV-2 infection and their potential impact on disease severity, suggesting androgen-targeting strategies might influence outcomes, but reports no new clinical results.
5 citations
,
January 2017 in “Endocrinology” This chapter reviews the biosynthesis, mechanism of action, and therapeutic effects of testosterone and related androgens, but reports no new research findings.
5 citations
,
December 2014 in “Polish Journal of Public Health” This review discusses the mechanisms of zinc transport, its role in human health, and the effects of zinc imbalance, without reporting new results.
5 citations
,
June 2010 in “Endocrinología y Nutrición” This article discusses PCOS in adolescents and highlights the importance of early diagnosis and treatment to prevent long-term health complications, noting increasing adolescent obesity may worsen symptoms.
5 citations
,
January 1984 in “Journal of psychosomatic obstetrics and gynecology/Journal of psychosomatic obstetrics and gynaecology” This study found that treatment with cyproterone acetate and ethinylestradiol in hirsute women reduced testosterone and androstenedione levels, decreased hair growth, and increased cortisol levels without changing catecholamine excretion.
4 citations
,
December 2021 in “Archivio italiano di urologia andrologia” This review found that patients taking antiandrogens, 5 alpha-reductase inhibitors, and spironolactone have an increased risk of developing gynecomastia, potentially due to hormonal changes.
4 citations
,
July 2017 in “Medicine” This article reviews the diagnosis and management of polycystic ovary syndrome, emphasizing lifestyle changes and treatment strategies, and reports no new clinical results.
4 citations
,
March 2017 in “Al-Mi’galaẗ al-sa'udiyaẗ lī-ulum al-ḥayaẗ” In this study, Leonuri Herba alkaloids significantly reduced prostate hyperplasia indicators and improved urinary parameters in hormone-induced model rats.
4 citations
,
November 2013 in “Journal of IMAB - Annual Proceeding (Scientific Papers)” This report presents a case of functioning adrenocortical oncocytoma in a 9-year-old girl with virilization symptoms, successfully treated with laparoscopic surgery.
4 citations
,
April 2013 in “Actas Dermo-Sifiliográficas” This study found that hairline measurements in white Spanish women differ from those previously reported for American women, which may be important for hair transplantation evaluations in alopecia cases.
4 citations
,
December 2012 in “Arquivos Brasileiros De Endocrinologia E Metabologia” A postmenopausal woman's masculine symptoms improved after surgery for a hormone-producing ovarian tumor.
3 citations
,
October 2022 in “International Journal of Impotence Research” This article reviews the role of testosterone in sexual health, supporting Testosterone Replacement Therapy as an effective treatment for Hypoactive Sexual Desire Disorder in postmenopausal women, though more research is needed on its long-term effects and applicability to premenopausal women.
3 citations
,
November 2021 in “Stress” This study found that school-related stress increases hair cortisol in girls and alters hair testosterone and cortisol levels in boys, indicating gender-specific hormonal responses to environmental changes.
3 citations
,
January 2016 in “Elsevier eBooks” This article discusses the various roles of steroids in vertebrate organ systems and notes several glucocorticoids that were among the Top 200 Drugs by sales in the 2010s, but it reports no new clinical findings.
3 citations
,
April 2015 in “American journal of biomedical sciences” This review discusses the molecular mechanisms of androgen action in human hair follicles and reports no new findings; the authors emphasize the need for further research to improve treatments for hair disorders.
3 citations
,
November 2005 in “Women's health” This narrative review discusses various causes and treatments of hirsutism in women, emphasizing the importance of identifying androgen-secreting tumors, but does not present new study results.
3 citations
,
August 2004 in “International journal of gynaecology and obstetrics” Finasteride doesn't change polycystic ovary size or cyst number, suggesting testosterone's role in their appearance.
3 citations
,
October 1995 in “International Journal of Dermatology” This study confirms that finasteride inhibits the conversion of testosterone to dihydrotestosterone in human dermal fibroblasts, suggesting potential therapeutic use for androgen-related skin disorders.
3 citations
,
December 2021 in “Physiological Research” This review discusses the potential link between androgen deficiency and increased COVID-19 severity in aging men, but reports no new clinical results; it suggests that low testosterone levels may pose a risk factor.
3 citations
,
September 2014 in “Journal of obstetrics and gynaecology Canada” Menopause often leads to lower sexual desire and discomfort during sex, but treatment should be personalized and only if it bothers the woman.
2 citations
,
January 2023 in “Research Square (Research Square)” This study found that obesity, insulin resistance, and hyperandrogenism increase the risk of depression and food cravings in women with PCOS, exacerbating obesity and metabolic syndrome.