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The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

High androgen levels in postmenopausal women may suggest an ovarian tumor, and removing it can improve heart and metabolic health.

A 20-year-old woman with a rare form of Turner syndrome showed improvement with hormonal therapy and needs comprehensive care.

The patient's long-term hair loss was caused by leukemia treatments and low estrogen levels, worsened by her genetic tendency for hair loss.

Oxidative stress and immune dysfunction are linked to both Hashimoto's thyroiditis and polycystic ovary syndrome, with diet and specific treatments important for managing these conditions.

Dutasteride, usually used for prostate issues and hair loss, could potentially treat Amyotrophic Lateral Sclerosis (ALS) due to its neuroprotective, antioxidant, and anti-inflammatory properties, but more testing is needed.

Early hormones shape sex-specific differences in rat glands.

Long-term use of finasteride in women can cause hormonal changes, DNA damage, and menstrual issues.

Women with PCOS have more depression and stress due to high androgen levels, not obesity or insulin resistance.

Hormones like androgens, estrogen, thyroid hormones, and stress hormones can contribute to hair loss, and treatments target these hormonal imbalances.

A brain-made hormone can protect against memory-related brain damage caused by harmful proteins.

A pineal tumor caused a boy's early puberty, which changed from peripheral to central after treatment.

Topical finasteride might be a good alternative for hair loss treatment with fewer side effects, but more research is needed.

Metformin lowers prolactin in women without PCOS but not in those with PCOS, where it reduces other hormones instead.

Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.

Androgen treatment with dihydrotestosterone may help maintain height in patients with 5-α-reductase type 2 deficiency, especially before puberty.

Blocking CRF1 receptors improved male hormone levels and reduced testicular tumor size in men with a specific adrenal condition.

The document concludes that personalized hormonal treatments are important for transgender individuals and more research is needed for non-binary treatments.

Congenital Adrenal Hyperplasia is a rare inherited disease causing hormone imbalances, affecting growth, fertility, and heart health, diagnosed through blood tests and treated with medication and lifestyle changes.

A toddler with a rare adrenal gland tumor causing male-like physical changes was successfully treated with surgery.

A man with X-ALD improved after treatment, highlighting the need to consider X-ALD in similar patients and test their relatives.

Managing side effects of endocrine therapy is crucial to improve adherence and survival in breast cancer patients.

Current alopecia treatments manage symptoms but don't cure, and better treatments are needed.

Red pigmented rice, like Sang-Yod rice, could help promote hair growth and prevent hair loss.

The study developed methods to measure biomarkers in mice and found differences in hormone levels linked to gut microbiota diversity and stress response.

Adding estrogen increased bone mass in a transsexual man undergoing hormone therapy.

Hormonal male contraception is effective and could be market-ready, but more research is needed to ensure safety for all ethnic groups.

Androgens can cause hair growth in some areas but hair loss on the scalp.

Androgens can both increase body hair and cause scalp hair loss.

Certain maturity signs appear before and after the first release of sperm in boys.