research Testosterone Deficiency Is Not Protective Against the Development of Adenocarcinoma of the Prostate in a Type 1 Diabetic Patient
Low testosterone does not prevent prostate cancer in men with type 1 diabetes.
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research The Role of Testosterone in SARS-CoV-2 Infection
Low testosterone levels may lead to more severe COVID-19 outcomes.
research Serum Testosterone Levels and Clinical Signs of Hypogonadism in Men with Type 2 Diabetes
Men with type 2 diabetes often have low testosterone and signs of hypogonadism, especially if they are overweight.
research Mechanisms of Testosterone Action
Testosterone works in different ways, including direct interaction with its receptor, conversion to other hormones for specific effects on genitalia, hair, bones, and muscle, and changes in body fat and sexual function when low.
research Intracrine Testosterone Activation in Human Pancreatic Beta Cells Stimulates Insulin Secretion
Testosterone in human pancreas cells boosts insulin production.
research Intracrine Testosterone Activation in Human Pancreatic Beta Cells Stimulates Insulin Secretion
Testosterone in our bodies helps increase insulin secretion from the pancreas.
research Decision Letter: Effects of Lifelong Testosterone Exposure on Health and Disease Using Mendelian Randomization
Increased free testosterone can lead to stronger bones and less body fat but also higher risks of prostate cancer, hair loss, spine issues, and high blood pressure.
research FDA-Approved (Bremelanotide, Flibanserin) and Off-Label Medications (Testosterone, Sildenafil) to Enhance Sexual Desire and Function in Women
Some medications can help increase sexual desire and function in women.
research Male Pattern Baldness and Waist-Hip Ratio as Markers of Arterial Stiffness in Transgender Men Undergoing Long-Term Testosterone Therapy
Male pattern baldness may indicate arterial stiffness in transgender men on long-term testosterone therapy.
research Testosterone Secreting Ovarian Tumor: A Rare Cause of Erythrocytosis and Pulmonary Embolus
A rare ovarian tumor that produced testosterone caused a blood clot in the lungs and increased red blood cells in a woman.
research Elevated Testosterone Secondary to Leydig Cell Hyperplasia in Bilateral Ovaries
A woman's high testosterone and related symptoms were caused by overactive cells in her ovaries.
research Protective Effect of Ellagic Acid on Testosterone-Induced Alopecia in Rats
Ellagic acid may help prevent hair loss caused by testosterone in rats.
research Effect of High Levels of Testosterone on Cardiovascular Risk in Polycystic Ovary Syndrome
High testosterone increases heart disease risk in women with PCOS.
research Detection of Cortisol, Estradiol, and Testosterone in Archaeological Human Hair from the Dakhleh Oasis, Egypt
Ancient hair can preserve hormones, revealing health and fertility insights.
research The Effect of Laparoscopic Ovarian Drilling on the Serum Levels of AMH, FSH, LH, and Testosterone Hormones in Patients with PCOS
Laparoscopic ovarian drilling helps infertile women with PCOS by improving menstrual regularity, ovulation, and chances of conception, and by changing hormone levels.
research Behavior of the Two Circulating Androgens Testosterone and DHEA and Their Main Intracellular Metabolites in an Androgen-Sensitive Sebocyte Cell Line
Testosterone affects androgen receptors and lipid storage in cells, while DHEA does not convert to testosterone or affect these receptors in the same way.
research Falsely Elevated Testosterone Levels: Role of LC-MS/MS in Reducing Unnecessary Testing
Using LC-MS/MS for hormone measurement can prevent false high testosterone results and avoid unnecessary tests.
research Novel Presentation of a Heterozygous INSR Mutation and Markedly Elevated Testosterone Levels in a Pediatric Patient: A Case Report
A young patient with unusual insulin resistance and high testosterone levels had a rare INSR gene mutation.
research Successful Virilization of a PAIS Patient with a Missense Mutation in the Ligand-Binding Domain of the Androgen Receptor Using Combined High-Dose Testosterone and Aromatase Inhibitor
A 12-year-old boy with PAIS successfully developed male characteristics using high-dose testosterone and anastrozole.
research Relationship Between Glucose Homeostatic Disorders and Testosterone in Adult Nigerian Women With Polycystic Ovary Syndrome
Higher testosterone levels in Nigerian women with PCOS are linked to glucose disorders like diabetes.
research Clomiphene Citrate and Human Chorionic Gonadotropin Are Both Effective in Restoring Testosterone in Hypogonadism: A Short-Course Randomized Study
Clomiphene citrate is a cheap and simple treatment for low testosterone that works as well as human chorionic gonadotropin, alone or combined, especially for men who want to keep their fertility.
research Clinical Improvements in Erectile Function and Mood in Hypogonadal Men Treated with 4.5% Nasal Testosterone Gel (Natesto)
Natesto nasal gel improves erectile function and mood in men with low testosterone within 30 days.
research Prostaglandin D2 Enhances Testosterone Metabolism by ROS-Mediated Altered Redox Potential in Keratinocytes
Prostaglandin D2 increases testosterone production in skin cells through a process involving reactive oxygen species, which could be a new target for treating hair loss and other skin conditions driven by testosterone.
research Testosterone Is Poorly Related to Erectile Dysfunction in Young and Middle-Aged HIV-Infected Men
Testosterone levels are not linked to erectile dysfunction in young and middle-aged men with HIV.
research Investigating the Mechanisms Underlying Effects of Testosterone on Blood Pressure in Normotensive and Hypertensive Rats
Testosterone raises blood pressure by affecting kidney function and brain gene regulation over time.
research Metastatic Embryonal Cell Carcinoma with High Testosterone and Absence of Secondary Sexual Characteristics
Treatment restored normal sexual characteristics and blood condition in a patient with testicular cancer.
research Testosterone-Secreting Tumor or Insulin Resistance? Metformin as a Diagnostic and Therapeutic Trial
Metformin can help diagnose and treat high testosterone levels in women, often due to insulin resistance rather than a tumor.
research FDA Declines Approval of Testosterone Drug for Third Time
The FDA did not approve a testosterone drug because of safety concerns.
research Effect of Testosterone Supplementation With and Without a Dual 5α-Reductase Inhibitor on Fat-Free Mass in Men with Suppressed Testosterone Production: A Randomized Controlled Trial
Testosterone increases muscle mass regardless of DHT conversion blocking.
research Testosterone and Female Sexuality: A Skeptical View
Testosterone's role in women's sex drive is unclear and needs more research, as low levels don't always mean less sexual interest and high levels can cause side effects.