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Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Early diagnosis and treatment, using finasteride, minoxidil, or hair transplantation, improves hair loss outcomes.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.

Hair loss in men is common, treatable, but not curable.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Cyproterone acetate-estrogen most effective for hirsutism, but consider side effects and patient needs.

Male pattern hair loss is genetic and influenced by hormones, with treatments like minoxidil and surgery available.

Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

Four-amino acid part makes enzyme sensitive to finasteride.

Acne treatment varies, with topical and systemic therapies effective, and more research needed on treatment order and long-term effects.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Certain medications including flutamide, spironolactone, and others effectively reduce excessive hair growth in women, especially when combined with lifestyle changes.

Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

Doctors need to be better prepared to assess and treat obesity in patients.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

People with polycystic ovary syndrome have a higher chance of having chronic thyroiditis.

Obese women with PCOS show a male-like pattern in certain fat tissue gene expressions.

Using finasteride or dutasteride may cause long-lasting erectile dysfunction.

Botox increased hair count in men with baldness and might work by improving scalp blood flow.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

The conclusion is that androgen receptor gene polymorphism might be a marker for polycystic ovary syndrome, but more research is needed.

New methods to make oxasteroids show promise for medical treatments like osteoporosis and breast cancer.

Women with only irregular periods or excess hair have a better hormone profile than those with full PCOS, but both groups are similar, indicating a need for better PCOS diagnosis methods.

Natural molecules like inositols, resveratrol, vitamins, and omega-3 fatty acids may help manage Polycystic Ovary Syndrome (PCOS), but their effects vary and need more exploration.