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Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

Certain drugs change freshwater snail shells to a "banana" shape.

Blood AMH levels are higher in women with PCOS than in those with other similar conditions.

Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.

Baldness in men with prostate cancer is linked to higher levels of certain sex hormones, but chest hair density is not.

LC-MS/MS is more reliable than immunoassays for diagnosing 21-hydroxylase deficiency.

Ovarian Leydig cell tumors are hard to diagnose with just advanced imaging; expert ultrasound and clinical evaluation are essential.

Blood tests can detect ovarian Leydig cell tumors when scans don't, and surgery can confirm and treat these tumors.

Women with PCOS have higher hair cortisol levels, which are linked to worse metabolic and inflammatory conditions.

PCOS is diagnosed when at least two of these three features are present: polycystic ovaries, irregular ovulation, and high androgen levels.

Heredity and hormones cause common hair loss, and topical minoxidil is the first recommended treatment.

N-acetylcysteine was more effective and had fewer side effects than metformin for improving insulin resistance in women with PCOS.

The document concludes that new treatments for hair loss may involve a combination of cosmetics, clinical methods, and genetic approaches.

Removing both ovaries treated the woman's excess male hormone symptoms.

Finasteride may decrease semen quality but not harm sperm production, and stopping the drug can improve semen quality; hyperprolactinemia can cause infertility but is treatable with medication.

Testosterone with finasteride improved muscle and bone health in men with spinal cord injury.

The research found that measuring androgens in urine can give extra information about body metabolism and is linked to androgen levels in the blood, especially in young girls.

Hair and nails can show hormone changes during puberty in dogs.

Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.

A rare ovarian cancer with a good outlook was found in a woman with unusual hair growth and abdominal symptoms.

The document concludes that ongoing medical therapy is crucial for preventing hair loss, and surgical options can restore hair, with future treatments for hair loss being promising.

The most effective treatments for hair loss are minoxidil, finasteride, PRP, and hair transplants, with steroids and immunosuppressants for autoimmune types.

A thorough initial check-up is essential before sperm banking to ensure the best chance of preserving good quality sperm.

Certain gene variations in AKT2 are more common in women with PCOS and are linked to higher levels of specific hormones and symptoms.

Men with early balding should be checked for metabolic syndrome, as there's a link between the two.

Hormones affect skin aging, and treatments targeting hormonal balance may improve skin health.

BRL 7660, once studied for male contraception, showed promise as an acne treatment but was not developed further due to competing drugs.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

The French Endocrine Society suggests diagnosing PCOS with two of three signs, recommends lifestyle changes and clomiphene for treatment, and calls for more research on certain treatments and tests.