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Quercetin may help with PCOS symptoms, but more research is needed.

Hormone therapy and surgeries for transgender individuals affect their skin and hair, requiring specific dermatologic treatments and respectful care.

Rutin may help treat symptoms of polycystic ovary syndrome (PCOS) in rats.

Stress from being transgender is linked to higher blood pressure at night and more inflammation, which may affect heart health.

Insulin-lowering medications show promise for PCOS symptoms but can't be the main treatment yet due to limited long-term research.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Men's hair loss is caused by hormones and genes, and can be treated with medication and surgery, while graying is due to aging and has no prevention except dyeing.

Genetic and environmental factors, like smoking and exercise, affect male hair loss.

The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.

The document explains hair biology, the causes of hair loss, and reviews various hair loss treatments.

Measuring reproductive hormones in brown bear hair could help identify their sex and reproductive state, but better collection methods or lab techniques are needed.

Some antiandrogens may lower testosterone better than others, but it's unclear which is best for feminization in transgender women; more research is needed.

The study found no link between baldness patterns and androgen levels in men with benign prostate enlargement or prostate cancer.

New treatments for hair loss show promise, especially finasteride for men and a stronger minoxidil formula.

Women with PCOS have unhealthy changes in their cholesterol particles that are not related to their body weight.

The normal human prostate does not significantly affect blood DHT levels.

Red deer only have androgen receptors in neck hair cells for mane growth during breeding season.

Androgenic steroids can slow down or stop the growth of certain skin fungi.

Male rats have androgen receptors in their liver, which are different from proteins that bind estrogen.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Transgender patients need proper skin care, especially when undergoing hormone treatments, to manage issues like acne and hair loss.

The review highlights the need for more research on transgender dermatology, the role of dermatologists in gender affirmation, and the effects of hormone therapy on skin and hair.

Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.

Both genetic and lifestyle factors significantly affect female hair loss.

Men with male pattern baldness have a higher risk of certain skin cancers, especially on the scalp.

Testosterone therapy helps boys with hormone deficiencies develop normal male characteristics and grow properly.

Male hormones cause different growth in identical human hair follicles due to their unique epigenetic characteristics.

Sex hormones like estrogen and testosterone may affect COVID-19 severity differently in men and women, potentially influencing prevention and treatment strategies.

Early medical support for transgender youth is important for their health, with low regret for gender-affirming hormone use and a need for knowledgeable care providers.

The document concludes that non-operative treatment for gender dysphoria is safe and effective, and hormone therapy does not increase cancer risk.