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Compounds 4, 4b, and 4c effectively inhibit an enzyme linked to testosterone conversion without significant toxicity.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

Isotretinoin and tazarotene help treat acne, while minoxidil and finasteride promote hair growth.

Low HDL-C, uric acid, and 25-hydroxyvitamin D are risk factors for early-onset male hair loss.

Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.

Anabolic steroids boost muscle growth, SARMs increase muscle mass and bone density without side effects, and myostatin inhibitors block a protein that stops muscle growth, but each has potential risks.

Statins may help treat PCOS by lowering androgen levels and improving cholesterol.

Metformin lowers prolactin in women without PCOS but not in those with PCOS, where it reduces other hormones instead.

Drugs can change hair growth and this is important because it can upset people.

Compound 15a was effective in inhibiting 5α-reductase.

Finasteride safely treats enlarged prostate and male-pattern baldness.

Scientists made a carbon-14 labeled version of a drug with a 48% yield and over 99% purity.

The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.

Oxidative stress plays a role in female pattern baldness, causing an imbalance between harmful and protective elements in the body.

The document reviews 20 U.S. patents from July and August 2004 about new drug forms, cancer treatments, aroma chemicals, statin drugs, and various chemical production methods.

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.

Rats had lasting erectile problems after stopping a certain medication.

Probe detects finasteride with high selectivity and low detection limit.

New hybrid compound found to effectively prevent hair loss.

A compound made by Pfizer can potentially stimulate hair growth and reduce oil production, making it a good candidate for topical use.

Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.

Vitamin D and estrogen may help protect heart and kidney health, and maintaining sufficient vitamin D levels could be especially beneficial for African Americans, postmenopausal women, and people with chronic kidney disease.

Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.

New tests detect finasteride and dutasteride in urine quickly and easily.

Flutamide, an antiandrogen, has minimal impact on female rat endocrine systems and does not significantly change their reproductive cycles.

Scientists made new substances that can block an enzyme linked to prostate issues and hair loss, with potential for creating a new treatment.

Finasteride blocks progesterone production in specific tumor cells, potentially causing side effects.

Rosuvastatin improves lipid levels, reduces inflammation, but worsens insulin sensitivity in men with early-onset hair loss.