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The conclusion is that individual differences in COVID-19 severity are influenced by factors like age, sex, race, and genetics, which are important for personalized medicine.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Obese women with PCOS show a male-like pattern in certain fat tissue gene expressions.

Nanocarrier-loaded gels improve drug delivery for cancer, skin conditions, and hair loss.

AMH helps estimate ovarian reserve but doesn't predict pregnancy chances; age is more important.

Botulinum toxin shows promise for various skin conditions but requires more research for confirmation and standardized use.

The document explains different types of hair loss, their causes, and treatments, and suggests future research areas.

Reduced AR gene methylation may cause early pubic hair growth in girls.

miR-22, a type of microRNA, controls hair growth and its overproduction can cause hair loss, while its absence can speed up hair growth.

Melatonin and mitotane treatment led to hair re-growth in 62% of dogs with Alopecia X, but this was not always linked to normal hormone levels.

The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.

BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.

Spironolactone improved blood vessel function and cholesterol levels in non-obese women with PCOS.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

Use "female pattern hair loss" term, assess androgen excess, treat with minoxidil and other medications if needed.

The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.

Essential oils from Chamaecyparis obtusa may help hair grow by increasing a growth-related gene.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

DHEA did not improve sexual function, well-being, or menopausal symptoms in postmenopausal women with low libido but caused side effects like acne and increased facial hair.

Hair follicles offer promising targets for delivering drugs to treat hair and skin conditions.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

People with polycystic ovary syndrome may have a higher risk of heart problems due to abnormal nervous system control of their heart and blood pressure.

To diagnose Polycystic Ovarian Syndrome, two out of three signs—irregular periods, high male hormone levels, or cysts on the ovaries—are needed.

Women with PCOS have similar levels of certain proteins compared to women without PCOS, and these proteins don't independently cause PCOS.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

Women with PCOS are more likely to have insulin resistance and obesity, especially those with the most severe type I PCOS.

Flutamide effectively treats female pattern hair loss with low doses showing good liver tolerance.