Search

everythinglearnresearchcommunity

for

Search:↓

Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.

Low-dose finasteride may cause fertility issues, but stopping it can improve sperm quality and lead to pregnancy.

Dutasteride and finasteride affect different cell types differently.

Phyllanthus urinaria extract may help treat hair loss by blocking a hair-related enzyme.

Finasteride safely treats enlarged prostate and male-pattern baldness.

New method accurately measures finasteride in tablets and bulk.

Researchers developed a method to measure different forms of a drug that could help treat prostate issues and hair loss, and found how these forms behave in animals.

Two new compounds can block androgen receptor activity in different ways and may lead to new treatments for androgen-related diseases.

Method detects finasteride in plasma at very low concentrations.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Cells from balding scalps have more androgen receptors than cells from non-balding scalps.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.

Different types of polycystic ovary syndrome (PCOS) have varying severity, with Type I being the most severe and common.

Finasteride effectively inhibits 5α reductase, while plant extracts like Permixon and Bazoton don't show significant results.

Male pattern baldness involves hormones and cell signals affecting hair growth.

Androgens have complex effects on hair growth, promoting it in some areas but causing hair loss in others, and our understanding of this is still evolving.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Finasteride effectively blocks rat enzymes, but with varying methods and strength.

New compounds called benzoquinolinones may treat conditions linked to excess DHT.

TGF-β1 from dermal papilla cells suppresses hair growth, and targeting it may help treat androgenetic alopecia.

Finasteride works better than Permixon in reducing dihydrotestosterone levels.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Edible seeds from the Cucurbitaceae family like pumpkin and watermelon seeds are nutritious and may have health benefits, but eating too much can cause side effects.

Syphilis can cause hair loss that looks like other conditions, but it improves with treatment.

Women with regular menstrual cycles and PCOS have linked kisspeptin and LH hormone patterns, unlike those with irregular cycles.

Higher IGF-1 levels in hair follicles link to better finasteride results for hair loss.

Finasteride-loaded nanoparticles may help treat alopecia.

Long-term finasteride use doesn't change bone density or metabolism.

Spironolactone plus finasteride reduces hirsutism more effectively.