research Predominant Expression of 5 Alpha-Reductase Type 1 in Pubic Skin from Normal Subjects and Hirsute Patients
The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.
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research Resveratrol Ameliorates the Seminiferous Tubules Damages Induced by Finasteride in Adult Male Rats
Resveratrol helps prevent finasteride-induced damage in male rats, improving reproductive function.
research Development of Prostate Cancer in a Patient with Primary Hypogonadism: Intratumoral Steroidogenesis in Prostate Cancer Tissues
Prostate cancer can progress even with low testosterone due to internal hormone production in the tumor.
research Serum 3α-Androstanediol-Glucuronide Is Decreased in Nonhirsute Women with Acne Vulgaris
Women with acne have lower levels of a specific hormone marker than women without acne.
research Mitochondria Dysfunction and Inflammation in Traumatic Brain Injury: Androgens to the Battlefront
Androgens like testosterone may help treat traumatic brain injury by reducing mitochondrial stress and inflammation.
research The Peptide AC 2 Isolated from Bacillus-Treated Trapa Japonica Fruit Extract Rescues DHT-Treated Human Dermal Papilla Cells and Mediates mTORC1 Signaling for Autophagy and Apoptosis Suppression
The AC 2 peptide from Trapa japonica fruit helps protect hair cells and may treat hair loss.
research Epicardial Fat Thickness in Children with Classic Congenital Adrenal Hyperplasia
Children with classic congenital adrenal hyperplasia have thicker heart fat and are at higher risk for heart problems and early atherosclerosis.
research Clinical and Laboratory Indicators of Polycystic Ovary Syndrome in Chinese Han Nationality with Different Rotterdam Criteria-Based Phenotypes
Different types of PCOS in Chinese Han women show varying levels of male hormone and metabolic issues.
research Androgen Receptor-Mediated Inhibition of Cutaneous Wound Healing
Blocking testosterone speeds up wound healing in males.
research An Attempt to Assess the Magnitude of Endogenous Androgen Production in a Case of the Adrenogenital Syndrome
A 17-year-old female with adrenogenital syndrome produces very high levels of androgens, which prevent complete feminization despite high estrogen doses.
research Role of 5α-Dihydrotestosterone in Testicular Development of Gilthead Seabream Following Finasteride Administration
DHT affects testicular development and regulates spermatogenesis in some fish.
research Adrenal Steroid Precursors Exert Potent Androgenic Action in the Hamster Sebaceous Glands of Flank Organs and Ears
Certain adrenal hormones can strongly stimulate oil gland growth in hamster skin, similar to male hormones.
research Circulating and Intraprostatic Sex Steroid Hormonal Profiles in Relation to Male Pattern Baldness and Chest Hair Density Among Men Diagnosed with Localized Prostate Cancers
Baldness in men with prostate cancer is linked to higher levels of certain sex hormones, but chest hair density is not.
research The Effect of Simvastatin on Plasma Steroid Hormone Levels in Metformin-Treated Women with Non-Classic Congenital Adrenal Hyperplasia
Simvastatin may help manage symptoms in women with non-classic congenital adrenal hyperplasia by lowering cholesterol and certain hormone levels.
research LC-MS/MS Improves Screening Towards 21-Hydroxylase Deficiency
LC-MS/MS is more reliable than immunoassays for diagnosing 21-hydroxylase deficiency.
research Morphogenetic Mechanisms in the Cyclic Regeneration of Hair Follicles and Deer Antlers from Stem Cells
Hair follicles and deer antlers regenerate similarly through stem cells and are influenced by hormones and growth factors.
research Adverse Effects of Sports Supplements in Men
Some sports supplements can cause health issues like mood swings, hair loss, and heart problems in men.
research Prenatal Androgenization of Ewes as a Model of Hirsutism in Polycystic Ovary Syndrome
Prenatally androgenized ewes can model increased hair diameter in women with PCOS.
research Prostate Specific Antigen in Diagnosis of Polycystic Ovarian Syndrome: A New Insight
PSA levels are higher in women with PCOS, but FAI is a more accurate marker for diagnosis.
research Effect of Saw Palmetto Supplements on Androgen-Sensitive LNCaP Human Prostate Cancer Cell Number and Syrian Hamster Flank Organ Growth
Saw palmetto supplements may reduce prostate cancer cell growth without being toxic.
research Effect of Finasteride on Ovulation Induction in Nonresponder (Hyperandrogenic) Polycystic Ovary Syndrome (PCOS) Women
Finasteride helps induce ovulation in nonresponder PCOS women.
research The Promoter of an Androgen Dependent Gene in the Hamster Flank Organ
Researchers found a gene in hamsters that responds to male hormones and may be indirectly controlled by them.
research Serum Preptin and Amylin Levels with Respect to Body Mass Index in Polycystic Ovary Syndrome Patients
Women with PCOS have lower amylin levels, which are not related to their body weight.
research Sertoli-Leydig Cell Tumors: Hormonal Profile After Dynamic Test with GnRH Analogue Triptorelin Represents a Useful Tool to Evaluate Tumoral Hyperandrogenism
Triptorelin helps evaluate hormone production in Sertoli-Leydig cell tumors.
research The Anti-Androgen Combination, Flutamide Plus Finasteride, Paradoxically Suppressed LH and Androgen Concentrations in Pregnant Spotted Hyenas, but Not in Males
Flutamide and finasteride reduced sex hormones in pregnant hyenas, but increased them in males.
research Polycystic Ovary Syndrome: Challenges in Adolescence
Diagnosing and managing PCOS in teens is hard, but early diagnosis and lifestyle changes are key, and more research is needed for long-term health.
research Parenteral and Oral Cyproterone Acetate Treatment in Severe Hirsutism
Cyproterone acetate implants were more effective at reducing facial hair and improving skin in severe hirsutism than oral treatment.
research The Cycle Characteristics and Outcomes of Infertile Nonclassic 21-Hydroxylase Deficiency Patients Undergoing Ovarian Stimulation for In Vitro Fertilization
Women with nonclassic 21-hydroxylase deficiency can have successful pregnancies through IVF, with certain factors affecting their chances.
research Evaluation of Serum Level of Omentin-1 in Females with Hirsutism
Women with hirsutism have different levels of omentin-1, which may be linked to the condition and its genetic aspects.
research Effects of Orlistat on Serum Androgen Levels Among Iranian Obese Women With Polycystic Ovarian Syndrome
Orlistat helped reduce weight and testosterone in obese women with PCOS but did not significantly affect other androgens or cholesterol levels.