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Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

5α-reductase inhibitors increase the risk of sexual dysfunction, especially in men with enlarged prostate.

Taking both finasteride and dutasteride for prostate issues may raise the risk of heart problems.

Taking 5-alpha reductase inhibitors does not increase the risk of breast cancer in men.

Finasteride effectively treats enlarged prostate and male baldness, improves symptoms of hirsutism in women, but doesn't work for acne, and may delay prostate cancer progression with few side effects.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.

Exercise improves insulin sensitivity and hormone regulation in PCOS rats.

Different skin cells process testosterone differently, and certain drugs can change this process, possibly helping treat acne and hair loss.

MENT could be a better option than testosterone for male hormone therapy and birth control because it works well at lower doses and has fewer side effects on the prostate.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Steroids, particularly estrogens and 5α-reductase inhibitors, affect blood vessel-related hair growth processes in hair follicle cells.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

Non-binary transgender individuals need personalized hormonal treatments for better well-being and quality of life.

Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Bee venom helps hair grow and may work better than some common treatments.

Finasteride reduces male rat fertility by causing issues with copulatory plug formation.

Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Cocaine impairs male sexual behavior and alters testosterone metabolism in the brain.

The normal human prostate does not significantly affect blood DHT levels.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

The nutritional supplement improved hair quality and reduced hair loss.

Reproductive gynecologists are the main referrers for male infertility evaluations in North America.

Androgens play a key role in hair growth and disorders like baldness and excessive hairiness.

The document concludes that proper diagnosis and tailored long-term treatment can effectively manage androgenic disorders in women, improving patient care outcomes.